Abstract
Seventeen children with unilateral hyperlucent lungs were referred for investigation. Of the 11 who had a referring diagnosis of possible Macleod's syndrome only two were shown to have post-viral bronchiolitis. Three of the 11 had conditions that required surgical treatment and a further two with brochiectasis were treated medically. To avoid confusion we suggest that Macleod's syndrome is reserved exclusively for children with post-viral bronchiolitis. Radioisotopic regional lung function studies were useful in the investigation of the subjects from three points of view. Firstly, they distinguished children with primary perfusion abnormalities and normal ventilation, secondly, they defined the extent of altered respiratory function, and thirdly, they were able to distinguish compensatory emphysema from congenital lobar emphysema. As bronchography and bronchoscopy may be hazardous in small children with poor respiratory reserve, such regional studies may be useful in indicating which patients do not require further invasive investigation.
Full text
PDFImages in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Cumming G. R., Macpherson R. I., Chernick V. Unilateral hyperlucent lung syndrome in children. J Pediatr. 1971 Feb;78(2):250–260. doi: 10.1016/s0022-3476(71)80008-2. [DOI] [PubMed] [Google Scholar]
- Lincoln J. C., Stark J., Subramanian S., Aberdeen E., Bonham-Carter R. E., Berry C. L., Waterston D. J. Congenital lobar emphysema. Ann Surg. 1971 Jan;173(1):55–62. doi: 10.1097/00000658-197101000-00008. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MACLEOD W. M. Abnormal transradiancy of one lung. Thorax. 1954 Jun;9(2):147–153. doi: 10.1136/thx.9.2.147. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Moser K. M., Guisan M., Cuomo A., Ashburn W. L. Differentiation of pulmonary vascular from parenchymal diseases by ventilation-perfusion scintiphotography. Ann Intern Med. 1971 Oct;75(4):597–605. doi: 10.7326/0003-4819-75-4-597. [DOI] [PubMed] [Google Scholar]
- Ronchetti R., Stocks J., Freedman N., Glass H., Godfrey S. Clinical application of regional lung function studies in infants and small children using 13N. Arch Dis Child. 1975 Aug;50(8):595–603. doi: 10.1136/adc.50.8.595. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SWYER P. R., JAMES G. C. A case of unilateral pulmonary emphysema. Thorax. 1953 Jun;8(2):133–136. doi: 10.1136/thx.8.2.133. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Shannon D. C., Todres I. D., Moylan F. M. Infantile lobar hyperinflation: expectant treatment. Pediatrics. 1977 Jun;59 (Suppl)(6 Pt 2):1012–1018. [PubMed] [Google Scholar]
- Stokes D., Sigler A., Khouri N. F., Talamo R. C. Unilateral hyperlucent lung (Swyer-James syndrome) after severe Mycoplasma pneumoniae infection. Am Rev Respir Dis. 1978 Jan;117(1):145–152. doi: 10.1164/arrd.1978.117.1.145. [DOI] [PubMed] [Google Scholar]
- Treves S., Ahnberg D. S., Laguarda R., Strieder D. J. Radionuclide evaluation of regional lung function in children. J Nucl Med. 1974 Jul;15(7):582–587. [PubMed] [Google Scholar]
- Wilson W. J., Amplatz K. Unequal vascularity in tetralogy of Fallot. Am J Roentgenol Radium Ther Nucl Med. 1967 Jun;100(2):318–321. doi: 10.2214/ajr.100.2.318. [DOI] [PubMed] [Google Scholar]