Skip to main content
PMC home page
Thorax logoLink to Thorax
. 1970 Jan;25(1):11–18. doi: 10.1136/thx.25.1.11

Inhalation experiments with extracts of Aspergillus fumigatus on patients with allergic aspergillosis and aspergilloma

E A M Stevens 1,2, C Hilvering 1,2, N G M Orie 1,2
PMCID: PMC472107  PMID: 4244699

Abstract

A description is given of the reaction to inhalation of Aspergillus extract by seven patients with aspergillosis, including five with aspergillomas. The nature of, and possible causes for, such reactions are discussed on the basis of their resemblance to the symptomatology of the vegetable dust syndromes. The findings may contribute to a better understanding of the pathogenesis of fever in aspergillosis.

Full text

PDF
13

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BISHOP J. M., MELNICK S. C., RAINE J. FARMER'S LUNG: STUDIES OF PULMONARY FUNCTION AND AETIOLOGY. Q J Med. 1963 Jul;32:257–278. [PubMed] [Google Scholar]
  2. BRINGHURST L. S., BYRNE R. N., GERSHON-COHEN J. Respiratory disease of mushroom workers; farmer's lung. J Am Med Assoc. 1959 Sep 5;171:15–18. doi: 10.1001/jama.1959.03010190017004. [DOI] [PubMed] [Google Scholar]
  3. Barrowcliff D. F., Arblaster P. G. Farmer's lung: a study of an early acute fatal case. Thorax. 1968 Sep;23(5):490–500. doi: 10.1136/thx.23.5.490. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. CAMPBELL M. J., CLAYTON Y. M. BRONCHOPULMONARY ASPERGILLOSIS. A CORRELATION OF THE CLINICAL AND LABORATORY FINDINGS IN 272 PATIENTS INVESTIGATED FOR BRONCHOPULMONARY ASPERGILLOSIS. Am Rev Respir Dis. 1964 Feb;89:186–196. doi: 10.1164/arrd.1964.89.2.186. [DOI] [PubMed] [Google Scholar]
  5. Dijkman J. H., Stevens E. A., Hilvering C., Orie N. G. Het aantonen van precipitinen in serum als hulpmiddel bij de diagnostiek van Aspergillusgroei in de long. Ned Tijdschr Geneeskd. 1968 Dec 28;112(52):2351–2357. [PubMed] [Google Scholar]
  6. EMANUEL D. A., LAWTON B. R., WENZEL F. J. Maple-bark disease. Pneumonitis due to Coniosporium corticale. N Engl J Med. 1962 Feb 15;26:333–337. [PubMed] [Google Scholar]
  7. FEINBERG J. G., TEMPLE A. An investigation on precipitins to moulds in asthmatic sera. Int Arch Allergy Appl Immunol. 1963;22:274–293. doi: 10.1159/000229371. [DOI] [PubMed] [Google Scholar]
  8. GERNEZ-RIEUX C., BIGUET J., VOISIN C., CAPRON A., BALGAIRIES E., TRANVANKY P. DIAGNOSTIC S'EROLOGIQUE DES ASPERGILLOMES BRONCHO-PULMONAIRES PAR IMMUNO-'ELECTROPHOR'ESE. J Fr Med Chir Thorac. 1963 Sep-Oct;17:663–676. [PubMed] [Google Scholar]
  9. GERNEZ-RIEUX C., BIGUET J., VOISIN C., CAPRON A., TRAN VAN KY P. [Immunological diagnosis of bronchopulmonary aspergillomas. Demonstration of specific serum antibodies by immunoelectrophoresis]. Presse Med. 1963 Jun 22;71:1541–1543. [PubMed] [Google Scholar]
  10. Hapke E. J., Seal R. M., Thomas G. O., Hayes M., Meek J. C. Farmer's lung. A clinical, radiographic, functional, and serological correlation of acute and chronic stages. Thorax. 1968 Sep;23(5):451–468. doi: 10.1136/thx.23.5.451. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Henderson A. H. Allergic aspergillosis: review of 32 cases. Thorax. 1968 Sep;23(5):501–512. doi: 10.1136/thx.23.5.501. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Hilvering C., Stevens E. A., Orie N. G. Fever in aspergillus mycetoma. Thorax. 1970 Jan;25(1):19–24. doi: 10.1136/thx.25.1.19. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Hilvering C., de Vries K., Orie N. G. Boerenlong ("farmer's lung"); longfunctioneel, allergologisch en serologisch onderzoek alsmede inhalatieproeven. Ned Tijdschr Geneeskd. 1966 Jul 16;110(29):1297–1307. [PubMed] [Google Scholar]
  14. LONGBOTTOM J. L., PEPYS J., CLIVE F. T. DIAGNOSTIC PRECIPITIN TEST IN ASPERGILLUS PULMONARY MYCETOMA. Lancet. 1964 Mar 14;1(7333):588–589. doi: 10.1016/s0140-6736(64)91335-2. [DOI] [PubMed] [Google Scholar]
  15. LONGBOTTOM J. L., PEPYS J. PULMONARY ASPERGILLOSIS: DIAGNOSTIC AND IMMUNOLOGICAL SIGNIFICANCE OF ANTIGENS AND C-SUBSTANCE IN ASPERGILLUS FUMIGATUS. J Pathol Bacteriol. 1964 Jul;88:141–151. doi: 10.1002/path.1700880119. [DOI] [PubMed] [Google Scholar]
  16. PARISH W. E. Farmer's lung. I. An immunological study of some antigenic components of mouldy foodstuffs. Thorax. 1963 Mar;18:83–89. doi: 10.1136/thx.18.1.83. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. PEPYS J., RIDDELL R. W., CITRON K. M., CLAYTON Y. M., SHORT E. I. Clinical and immunologic significance of Aspergillus fumigatus in the sputum. Am Rev Respir Dis. 1959 Aug;80:167–180. doi: 10.1164/arrd.1959.80.2.167. [DOI] [PubMed] [Google Scholar]
  18. REED C. E., BARBEE R. A. PIGEON-BREEDERS' LUNG: A NEWLY OBSERVED INTERSTITIAL PULMONARY DISEASE. JAMA. 1965 Jul 26;193:261–265. doi: 10.1001/jama.1965.03090040005001. [DOI] [PubMed] [Google Scholar]
  19. Seal R. M., Hapke E. J., Thomas G. O., Meek J. C., Hayes M. The pathology of the acute and chronic stages of farmer's lung. Thorax. 1968 Sep;23(5):469–489. doi: 10.1136/thx.23.5.469. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Thorax are provided here courtesy of BMJ Publishing Group

RESOURCES