Skip to main content
PMC home page
Thorax logoLink to Thorax
. 1970 Nov;25(6):665–668. doi: 10.1136/thx.25.6.665

Surgery of ventricular septal defect and pulmonary vascular resistance

H A Samaan 1
PMCID: PMC472208  PMID: 5494676

Abstract

In a series of 65 patients operated upon for ventricular septal defects (VSD), no mortality was attributed to pre-operative raised pulmonary vascular resistance. Eight patients with a severe degree of pulmonary vascular resistance made a full recovery after surgical closure of the ventricular septal defect. Three patients were cyanotic at the time of operation. Mortality in the series was the result of inadequate perfusion during operation, haemorrhage, cardiac tamponade, mediastinal infection, complete heart block or the development of post-operative aortic incompetence. Raised pulmonary vascular resistance and clinical evidence of a dominant left-to-right shunt in the absence of serious intracardiac anatomical complications does not contraindicate surgery for the repair of VSD.

Full text

PDF
668

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Cartmill T. B., DuShane J. W., McGoon D. C., Kirklin J. W. Results of repair of ventricular septal defect. J Thorac Cardiovasc Surg. 1966 Oct;52(4):486–501. [PubMed] [Google Scholar]
  2. EDWARDS J. E. Functional pathology of the pulmonary vascular tree in congenital cardiac disease. Circulation. 1957 Feb;15(2):164–196. doi: 10.1161/01.cir.15.2.164. [DOI] [PubMed] [Google Scholar]
  3. GOLDBLATT A., BERNHARD W. F., NADAS A. S., GROSS R. E. PULMONARY ARTERY BANDING: INDICATIONS AND RESULTS IN INFANTS AND CHILDREN. Circulation. 1965 Aug;32:172–184. doi: 10.1161/01.cir.32.2.172. [DOI] [PubMed] [Google Scholar]
  4. HEATH D., EDWARDS J. E. The pathology of hypertensive pulmonary vascular disease; a description of six grades of structural changes in the pulmonary arteries with special reference to congenital cardiac septal defects. Circulation. 1958 Oct;18(4 Pt 1):533–547. doi: 10.1161/01.cir.18.4.533. [DOI] [PubMed] [Google Scholar]
  5. HEATH D., HELMHOLZ H. F., Jr, BURCHELL H. B., DUSHANE J. W., KIRKLIN J. W., EDWARDS J. E. Relation between structural change in the small pulmonary arteries and the immediate reversibility of pulmonary hypertension following closure of ventricular and atrial septal defects. Circulation. 1958 Dec;18(6):1167–1174. doi: 10.1161/01.cir.18.6.1167. [DOI] [PubMed] [Google Scholar]
  6. Hallidie-Smith K. A., Hollman A., Cleland W. P., Bentall H. H., Goodwin J. F. Effects of surgical closure of ventricular septal defects upon pulmonary vascular disease. Br Heart J. 1969 Mar;31(2):246–260. doi: 10.1136/hrt.31.2.246. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Hoffman J. I. Natural history of congenital heart disease. Problems in its assessment with special reference to ventricular septal defects. Circulation. 1968 Jan;37(1):97–125. doi: 10.1161/01.cir.37.1.97. [DOI] [PubMed] [Google Scholar]
  8. MULLER W. H., Jr, DANIMANN J. F., Jr The treatment of certain congenital malformations of the heart by the creation of pulmonic stenosis to reduce pulmonary hypertension and excessive pulmonary blood flow; a preliminary report. Surg Gynecol Obstet. 1952 Aug;95(2):213–219. [PubMed] [Google Scholar]
  9. Vogel J. H., McNamara D. G., Blount S. G., Jr Role of hypoxia in determining pulmonary vascular resistance in infants with ventricular septal defects. Am J Cardiol. 1967 Sep;20(3):346–349. doi: 10.1016/0002-9149(67)90056-2. [DOI] [PubMed] [Google Scholar]
  10. WAGENVOORT C. A., NEUFELD H. N., DUSHANE J. W., EDWARDS J. E. The pulmonary arterial tree in ventricular septal defect. A quantitative study of anatomic features in fetuses, infants. and children. Circulation. 1961 May;23:740–748. doi: 10.1161/01.cir.23.5.740. [DOI] [PubMed] [Google Scholar]

Articles from Thorax are provided here courtesy of BMJ Publishing Group

RESOURCES