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. 1970 Nov;25(6):691–701. doi: 10.1136/thx.25.6.691

Necrotizing pulmonary aspergillosis

W P U Kennedy 1,2,3,4, D N Malone 1,2,3,4, W Blyth 1,2,3,4
PMCID: PMC472211  PMID: 5533320

Abstract

Necrotizing or invasive aspergillary infection of the lungs has previously been considered a rare condition affecting only the debilitated or seriously ill. Four patients with necrotizing pulmonary aspergillosis are described, and the mycological and histopathological findings are discussed. The diagnosis in the first patient was not made until necropsy, following death from fulminating pulmonary infection. Of three patients treated with natamycin, two made a satisfactory recovery; the other died later from bronchial carcinoma. Previous multiple antibiotic therapy in each case may have been a contributory factor to infection with Aspergillus fumigatus. We suggest that fungal infection of the lungs should be actively sought in patients with pulmonary disease, especially in those receiving multiple antibiotic or corticosteroid therapy.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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