Skip to main content
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1967 Jan;20(1):49–51. doi: 10.1136/jcp.20.1.49

Possibility of normokalaemic primary aldosteronism as reflected in the frequency of adrenal cortical adenomas

I Dévényi 1
PMCID: PMC473419  PMID: 6016887

Abstract

Adrenal cortical adenomas with diameters greater than 3 mm. were found in 185 (3·61%, of 5,120 consecutive necropsies. A progressively higher incidence with increasing age was noted) 82% of the adenomas occurring in cases in the age range 51-80 years.

On the basis of age distribution of adenomas and their connexion with hypertension, there does not seem to be sufficient proof to suppose that the cortical adenomas frequently found at necropsy can be held responsible for causing normokalaemic primary aldosteronism to the extent assumed by Conn (1964).

Full text

PDF
50

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CONN J. W., COHEN E. L., ROVNER D. R., NESBIT R. M. NORMOKALEMIC PRIMARY ALDOSTERONISM. A DETECTABLE CAUSE OF CURABLE "ESSENTIAL" HYPERTENSION. JAMA. 1965 Jul 19;193:200–206. doi: 10.1001/jama.1965.03090030022005. [DOI] [PubMed] [Google Scholar]
  2. CONN J. W., COHEN E. L., ROVNER D. R. SUPPRESSION OF PLASMA RENIN ACTIVITY IN PRIMARY ALDOSTERONISM. JAMA. 1964 Oct 19;190:213–221. doi: 10.1001/jama.1964.03070160037008. [DOI] [PubMed] [Google Scholar]
  3. CONN J. W., ROVNER D. R., COHEN E. L. NORMAL AND ALTERED FUNCTION OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM IN MAN: APPLICATIONS IN CLINICAL AND RESEARCH MEDICINE. Ann Intern Med. 1965 Aug;63:266–284. doi: 10.7326/0003-4819-63-2-266. [DOI] [PubMed] [Google Scholar]
  4. Cohen R. B. Observations of cortical nodules in human adrenal glands. Their relationship to neoplasia. Cancer. 1966 Apr;19(4):552–556. doi: 10.1002/1097-0142(196604)19:4<552::aid-cncr2820190414>3.0.co;2-l. [DOI] [PubMed] [Google Scholar]
  5. SHAMMA A. H., GODDARD J. W., SOMMERS S. C. A study of the adrenal status in hypertension. J Chronic Dis. 1958 Nov;8(5):587–595. doi: 10.1016/0021-9681(58)90051-1. [DOI] [PubMed] [Google Scholar]
  6. SHERWIN R. P. PRESENT STATUS OF THE PATHOLOGY OF THE ADRENAL GLAND IN HYPERTENSION. Am J Surg. 1964 Jan;107:136–143. doi: 10.1016/0002-9610(64)90249-1. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES