Skip to main content
PMC home page
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1967 Nov;20(6):865–869. doi: 10.1136/jcp.20.6.865

Mycoplasmas and recurrent oral ulceration

A M Gordon 1,2, H M Dick 1,2, D K Mason 1,2, W Manderson 1,2, W B Crichton 1,2
PMCID: PMC473628  PMID: 5614072

Abstract

A controlled cultural and serological investigation of mycoplasmas in recurrent oral ulceration was undertaken. No evidence for an aetiological relationship between oral mycoplasmas and this condition was obtained.

Mycoplasmas, principally M. orale, were frequently recovered from the oral cavities of individuals with natural teeth, but rarely from edentulous subjects.

Full text

PDF
869

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Andrews B. E. Mycoplasma Species as Agents of Disease in Animals and Man [Abridged]. Proc R Soc Med. 1965 Feb;58(2):80–82. [PMC free article] [PubMed] [Google Scholar]
  2. BARILE M. F., GRAYKOWSKI E. A., DRISCOLL E. J., RIGGS D. B. L FORM OF BACTERIA ISOLATED FROM RECURRENT APHTHOUS STOMATITIS LESIONS. Oral Surg Oral Med Oral Pathol. 1963 Nov;16:1395–1402. doi: 10.1016/0030-4220(63)90416-x. [DOI] [PubMed] [Google Scholar]
  3. BARILE M. F., SHEINGORN A. The isolation and cultivation of a filterable form resembling pleuropneumonia-like organisms from the human dental pulp: report of a case. Oral Surg Oral Med Oral Pathol. 1960 Jun;13:756–760. doi: 10.1016/0030-4220(60)90378-9. [DOI] [PubMed] [Google Scholar]
  4. BURNETT G. W., GILMORE E. Incidence and distribution of oral pleuropneumonialike and L organisms. J Dent Res. 1959 May-Jun;38(3):632–632. doi: 10.1177/00220345590380032901. [DOI] [PubMed] [Google Scholar]
  5. CHANOCK R. M., JAMES W. D., FOX H. H., TURNER H. C., MUFSON M. A., HAYFLICK L. Growth of Eaton PPLO in broth and preparation of complement fixing antigen. Proc Soc Exp Biol Med. 1962 Aug-Sep;110:884–889. doi: 10.3181/00379727-110-27681. [DOI] [PubMed] [Google Scholar]
  6. CLYDE W. A., Jr MYCOPLASMA SPECIES IDENTIFICATION BASED UPON GROWTH INHIBITION BY SPECIFIC ANTISERA. J Immunol. 1964 Jun;92:958–965. [PubMed] [Google Scholar]
  7. DOWDLE W. R., ROBINSON R. Q. AN INDIRECT HEMAGGLUTINATION TEST FOR DIAGNOSIS OF MYCOPLASMA PNEUMONIAE INFECTIONS. Proc Soc Exp Biol Med. 1964 Aug-Sep;116:947–950. doi: 10.3181/00379727-116-29416. [DOI] [PubMed] [Google Scholar]
  8. Decker J. L., Ward J. R. The relationship of mycoplasma (PPLO) to Rheumatoid arthritis and related diseases: a working conference. Bull Rheum Dis. 1966 May;16(9):412–413. [PubMed] [Google Scholar]
  9. FORD D. K. Rheumatoid arthritis--an infection? Arthritis Rheum. 1963 Apr;6:159–165. doi: 10.1002/art.1780060207. [DOI] [PubMed] [Google Scholar]
  10. FORSYTH B. R., BLOOM H. H., JOHNSON K. M., CHANOCK R. M. ETIOLOGY OF PRIMARY ATYPICAL PNEUMONIA IN A MILITARY POPULATION. JAMA. 1965 Feb 1;191:364–368. doi: 10.1001/jama.1965.03080050010002. [DOI] [PubMed] [Google Scholar]
  11. FRIEDMAN M., BENNETT C. R. A hemagglutination test for detection of adenovirus antibodies. Proc Soc Exp Biol Med. 1957 Apr;94(4):712–717. doi: 10.3181/00379727-94-23062. [DOI] [PubMed] [Google Scholar]
  12. Feizi T., Maclean H., Sommerville R. G., Selwyn J. G. Studies on an epidemic of respiratory disease caused by Mycoplasma pneumoniae. Br Med J. 1967 Feb 25;1(5538):457–460. doi: 10.1136/bmj.1.5538.457. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. GOODBURN G. M., MARMION B. P., KENDALL E. J. Infection with Eaton's primary atypical pneumonia agent in England. Br Med J. 1963 May 11;1(5340):1266–1270. doi: 10.1136/bmj.1.5340.1266. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. GRAYKOWSKI E. A., BARILE M. F., STANLEY H. R. PERIADENITIS APHTHAE: CLINICAL AND HISTOPATHOLOGIC ASPECTS OF LESIONS IN A PATIENT AND OF LESIONS PRODUCED IN RABBIT SKIN. J Am Dent Assoc. 1964 Aug;69:118–126. doi: 10.14219/jada.archive.1964.0242. [DOI] [PubMed] [Google Scholar]
  15. GRAYSTON J. T., ALEXANDER E. R., KENNY G. E., CLARKE E. R., FREMONT J. C., MACCOLL W. A. MYCOPLASMA PNEUMONIAE INFECTIONS. CLINICAL AND EPIDEMIOLOGIC STUDIES. JAMA. 1965 Feb 1;191:369–374. doi: 10.1001/jama.1965.03080050015004. [DOI] [PubMed] [Google Scholar]
  16. Graykowski E. A., Barile M. F., Lee W. B., Stanley H. R., Jr Recurrent aphthous stomatitis. Clinical, therapeutic, histopathologic, and hypersensitivity aspects. JAMA. 1966 May 16;196(7):637–644. doi: 10.1001/jama.196.7.637. [DOI] [PubMed] [Google Scholar]
  17. HAYFLICK L., CHANOCK R. M. MYCOPLASMA SPECIES OF MAN. Bacteriol Rev. 1965 Jun;29:185–221. doi: 10.1128/br.29.2.185-221.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. KAPLAN M. H. IMMUNOLOGIC RELATION OF STREPTOCOCCAL AND TISSUE ANTIGENS. I. PROPERTIES OF AN ANTIGEN IN CERTAIN STRAINS OF GROUP A STREPTOCOCCI EXHIBITING AN IMMUNOLOGIC CROSS-REACTION WITH HUMAN HEART TISSUE. J Immunol. 1963 Apr;90:595–606. [PubMed] [Google Scholar]
  19. KRAMER I. R. 'APHTHOUS' AND HERPETIC LESIONS OF THE ORAL MUCOSA. Proc R Soc Med. 1965 Jun;58:458–462. [PMC free article] [PubMed] [Google Scholar]
  20. LEHNER T. RECURRENT APHTHOUS ULCERATION AND AUTOIMMUNITY. Lancet. 1964 Nov 28;2(7370):1154–1155. doi: 10.1016/s0140-6736(64)92673-x. [DOI] [PubMed] [Google Scholar]
  21. LIU C. Studies on primary atypical pneumonia. I. Localization, isolation, and cultivation of a virus in chick embryos. J Exp Med. 1957 Oct 1;106(4):455–466. doi: 10.1084/jem.106.4.455. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Lehner T., Sagebiel R. W. Fine structural findings in recurrent oral ulceration. Br Dent J. 1966 Nov 15;121(10):454–456. [PubMed] [Google Scholar]
  23. MORTON H. E., SMITH P. F., WILLIAMS N. B., EICKENBERG C. F. Isolation of pleuropneumonia-like organisms from human saliva: a newly detection member of the oral flora. J Dent Res. 1951 Jun;30(3):415–422. doi: 10.1177/00220345510300031701. [DOI] [PubMed] [Google Scholar]
  24. MUFSON M. A., LUDWIG W. M., PURCELL R. H., CATE T. R., TAYLOR-ROBINSON D., CHANOCK R. M. EXUDATIVE PHARYNGITIS FOLLOWING EXPERIMENTAL MYCOPLASMA HOMINIS: TYPE 1 INFECTION. JAMA. 1965 Jun 28;192:1146–1152. doi: 10.1001/jama.1965.03080260034010. [DOI] [PubMed] [Google Scholar]
  25. OATES J. K., WHITTINGTON M. J., WILKINSON A. E. A note on the results of cultural and serological tests for pleuropneumonia-like organisms in Reiter's disease. Br J Vener Dis. 1959 Sep;35:184–186. doi: 10.1136/sti.35.3.184. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Perlmann P., Hammarström S., Lagercrantz R., Gustafsson B. E. Antigen from colon of germfree rats and antibodies in human ulcerative colitis. Ann N Y Acad Sci. 1965 Jun 30;124(1):377–394. doi: 10.1111/j.1749-6632.1965.tb18972.x. [DOI] [PubMed] [Google Scholar]
  27. SCOTT R. B. ORAL ULCERATION. MEDICAL ASPECTS. Proc R Soc Med. 1965 Jun;58:453–455. [PMC free article] [PubMed] [Google Scholar]
  28. SHIP I. I., MERRITT A. D., STANLEY H. R. Recurrent aphthous ulcers. Am J Med. 1962 Jan;32:32–43. doi: 10.1016/0002-9343(62)90180-8. [DOI] [PubMed] [Google Scholar]
  29. SHKLAIR I. L., MAZZARELLA M. A., GUTEKUNST R. R., KIGGINS E. M. Isolation and incidence of pleuropneumonia-like organisms from the human oral cavity. J Bacteriol. 1962 Apr;83:785–788. doi: 10.1128/jb.83.4.785-788.1962. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. SIRCUS W., CHURCH R., KELLEHER J. Recurrent aphthous ulceration of the mouth; a study of the natural history, aetiology, and treatment. Q J Med. 1957 Apr;26(102):235–249. [PubMed] [Google Scholar]
  31. SMITH P. F., MORTON H. E. Isolation of pleuropneumonialike organisms from the throats of humans. Science. 1951 Jun 1;113(2944):623–624. doi: 10.1126/science.113.2944.623. [DOI] [PubMed] [Google Scholar]
  32. TAYLOR-ROBINSON D., CANCHOLA J., FOX H., CHANOCK R. M. A NEWLY IDENTIFIED ORAL MYCOPLASMA (M. ORALE) AND ITS RELATIONSHIP TO OTHER HUMAN MYCOPLASMAS. Am J Hyg. 1964 Jul;80:135–148. doi: 10.1093/oxfordjournals.aje.a120454. [DOI] [PubMed] [Google Scholar]
  33. TAYLOR-ROBINSON D., CHANOCK R. M. CHARACTERIZATION OF A NEWLY IDENTIFIED MYCOPLASMA FROM THE HUMAN OROPHARYNX. Am J Epidemiol. 1965 Mar;81:180–191. doi: 10.1093/oxfordjournals.aje.a120506. [DOI] [PubMed] [Google Scholar]
  34. TAYLOR-ROBINSON D., LUDWIG W. M., PURCELL R. H., MUFSON M. A., CHANOCK R. M. SIGNIFICANCE OF ANTIBODY TO MYCOPLASMA HOMINIS TYPE 1 AS MEASURED BY INDIRECT HEMAGGLUTINATION. Proc Soc Exp Biol Med. 1965 Apr;118:1073–1083. doi: 10.3181/00379727-118-30049. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES