Skip to main content
PMC home page
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1968 Jul;21(4):511–517. doi: 10.1136/jcp.21.4.511

Evaluation of discordant laboratory data in patients with thyroid disorders

J A Thomson 1, I T Boyle 1, E M McGirr 1, E M Macdonald 1, J Nicol 1, J Brown 1
PMCID: PMC473844  PMID: 4177096

Abstract

The usefulness of the various tests of thyroid function has been evaluated over a three-year period. It is concluded that an uptake test and estimation of the serum protein-bound radioactive iodine (PB 131I), supplemented as required by the protein-bound iodine (PBI), remain the best routine tests of thyroid function. Forty-five patients who gave discordant results on these tests over this period have been studied in detail and the value of other tests of thyroid function has been explored.

Full text

PDF
516

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ANDERSON J. R., BUCHANAN W. W., GOUDIE R. B., GRAY K. G. Diagnostic tests for thyroid antibodies: a comparison of the precipitin and latex-fixation (Hyland TAI) tests. J Clin Pathol. 1962 Sep;15:462–471. doi: 10.1136/jcp.15.5.462. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Alexander W. D., Harden R. M., Koutras D. A., Wayne E. Influence of iodine intake after treatment with antithyroid drugs. Lancet. 1965 Oct 30;2(7418):866–868. doi: 10.1016/s0140-6736(65)92501-8. [DOI] [PubMed] [Google Scholar]
  3. CAVALIERI R. R. Hyperthyroidism and decreased thyroxine binding by serum proteins. J Clin Endocrinol Metab. 1961 Nov;21:1455–1468. doi: 10.1210/jcem-21-11-1455. [DOI] [PubMed] [Google Scholar]
  4. CLARK F., HORN D. B. ASSESSMENT OF THYROID FUNCTION BY THE COMBINED USE OF THE SERUM PROTEIN-BOUND IODINE AND RESIN UPTAKE OF 131-I-TRIIODOTHYRONINE. J Clin Endocrinol Metab. 1965 Jan;25:39–45. doi: 10.1210/jcem-25-1-39. [DOI] [PubMed] [Google Scholar]
  5. FARRELL L. P., RICHMOND M. H. A rapid method for the estimation of serum protein-bound iodine. Clin Chim Acta. 1961 Sep;6:620–623. doi: 10.1016/0009-8981(61)90104-8. [DOI] [PubMed] [Google Scholar]
  6. MURRAY I. P., MCGIRR E. M. Radioactive iodine studies in the diagnosis of Hashimoto's thyroiditis. Br Med J. 1960 Mar 19;1(5176):838–841. doi: 10.1136/bmj.1.5176.838. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. OPPENHEIMER J. H., SQUEF R., SURKS M. I., HAUER H. BINDING OF THYROXINE BY SERUM PROTEINS EVALUATED BY EQUILIBRUM DIALYSIS AND ELECTROPHORETIC TECHNIQUES. ALTERATIONS IN NONTHYROIDAL ILLNESS. J Clin Invest. 1963 Nov;42:1769–1782. doi: 10.1172/JCI104862. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. OSORIO C., JACKSON D. J., GARTSIDE J. M., GOOLDEN A. W. The uptake of 131-I triiodothyronine by red cells in relation to the binding of thyroid hormones in plasma proteins. Clin Sci. 1961 Dec;21:355–365. [PubMed] [Google Scholar]
  9. WAYNE E. J. Clinical and metabolic studies in thyroid disease. Br Med J. 1960 Jan 2;1(5165):1–11. doi: 10.1136/bmj.1.5165.1. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES