Skip to main content
Thorax logoLink to Thorax
editorial
. 1995 Feb;50(2):111–112. doi: 10.1136/thx.50.2.111

Lipoxin A4: a novel anti-inflammatory molecule?

T H Lee
PMCID: PMC473888  PMID: 7701445

Full text

PDF

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Arm J. P., O'Hickey S. P., Spur B. W., Lee T. H. Airway responsiveness to histamine and leukotriene E4 in subjects with aspirin-induced asthma. Am Rev Respir Dis. 1989 Jul;140(1):148–153. doi: 10.1164/ajrccm/140.1.148. [DOI] [PubMed] [Google Scholar]
  2. Arm J. P., Spur B. W., Lee T. H. The effects of inhaled leukotriene E4 on the airway responsiveness to histamine in subjects with asthma and normal subjects. J Allergy Clin Immunol. 1988 Oct;82(4):654–660. doi: 10.1016/0091-6749(88)90979-7. [DOI] [PubMed] [Google Scholar]
  3. Borgeat P., Samuelsson B. Arachidonic acid metabolism in polymorphonuclear leukocytes: effects of ionophore A23187. Proc Natl Acad Sci U S A. 1979 May;76(5):2148–2152. doi: 10.1073/pnas.76.5.2148. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Borgeat P., Samuelsson B. Metabolism of arachidonic acid in polymorphonuclear leukocytes. Structural analysis of novel hydroxylated compounds. J Biol Chem. 1979 Aug 25;254(16):7865–7869. [PubMed] [Google Scholar]
  5. Christie P. E., Spur B. W., Lee T. H. The effects of lipoxin A4 on airway responses in asthmatic subjects. Am Rev Respir Dis. 1992 Jun;145(6):1281–1284. doi: 10.1164/ajrccm/145.6.1281. [DOI] [PubMed] [Google Scholar]
  6. Cirino G., Peers S. H., Flower R. J., Browning J. L., Pepinsky R. B. Human recombinant lipocortin 1 has acute local anti-inflammatory properties in the rat paw edema test. Proc Natl Acad Sci U S A. 1989 May;86(9):3428–3432. doi: 10.1073/pnas.86.9.3428. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Dahlén S. E., Franzén L., Raud J., Serhan C. N., Westlund P., Wikström E., Björck T., Matsuda H., Webber S. E., Veale C. A. Actions of lipoxin A4 and related compounds in smooth muscle preparations and on the microcirculation in vivo. Adv Exp Med Biol. 1988;229:107–130. doi: 10.1007/978-1-4757-0937-7_9. [DOI] [PubMed] [Google Scholar]
  8. Dahlén S. E., Raud J., Serhan C. N., Björk J., Samuelsson B. Biological activities of lipoxin A include lung strip contraction and dilation of arterioles in vivo. Acta Physiol Scand. 1987 Aug;130(4):643–647. doi: 10.1111/j.1748-1716.1987.tb08187.x. [DOI] [PubMed] [Google Scholar]
  9. Grandordy B. M., Lacroix H., Mavoungou E., Krilis S., Crea A. E., Spur B. W., Lee T. H. Lipoxin A4 inhibits phosphoinositide hydrolysis in human neutrophils. Biochem Biophys Res Commun. 1990 Mar 30;167(3):1022–1029. doi: 10.1016/0006-291x(90)90625-w. [DOI] [PubMed] [Google Scholar]
  10. Hamberg M., Samuelsson B. Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets. Proc Natl Acad Sci U S A. 1974 Sep;71(9):3400–3404. doi: 10.1073/pnas.71.9.3400. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Hedqvist P., Raud J., Palmertz U., Haeggström J., Nicolaou K. C., Dahlén S. E. Lipoxin A4 inhibits leukotriene B4-induced inflammation in the hamster cheek pouch. Acta Physiol Scand. 1989 Dec;137(4):571–572. doi: 10.1111/j.1748-1716.1989.tb08805.x. [DOI] [PubMed] [Google Scholar]
  12. Jacques C. A., Spur B. W., Crea A. E., Lee T. H. The contractile activities of lipoxin A4 and lipoxin B4 for guinea-pig airway tissues. Br J Pharmacol. 1988 Oct;95(2):562–568. doi: 10.1111/j.1476-5381.1988.tb11677.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Lam S., Chan H., LeRiche J. C., Chan-Yeung M., Salari H. Release of leukotrienes in patients with bronchial asthma. J Allergy Clin Immunol. 1988 Apr;81(4):711–717. doi: 10.1016/0091-6749(88)91043-3. [DOI] [PubMed] [Google Scholar]
  14. Lee T. H., Crea A. E., Gant V., Spur B. W., Marron B. E., Nicolaou K. C., Reardon E., Brezinski M., Serhan C. N. Identification of lipoxin A4 and its relationship to the sulfidopeptide leukotrienes C4, D4, and E4 in the bronchoalveolar lavage fluids obtained from patients with selected pulmonary diseases. Am Rev Respir Dis. 1990 Jun;141(6):1453–1458. doi: 10.1164/ajrccm/141.6.1453. [DOI] [PubMed] [Google Scholar]
  15. Lee T. H., Horton C. E., Kyan-Aung U., Haskard D., Crea A. E., Spur B. W. Lipoxin A4 and lipoxin B4 inhibit chemotactic responses of human neutrophils stimulated by leukotriene B4 and N-formyl-L-methionyl-L-leucyl-L-phenylalanine. Clin Sci (Lond) 1989 Aug;77(2):195–203. doi: 10.1042/cs0770195. [DOI] [PubMed] [Google Scholar]
  16. Lee T. H., Lympany P., Crea A. E., Spur B. W. Inhibition of leukotriene B4-induced neutrophil migration by lipoxin A4: structure-function relationships. Biochem Biophys Res Commun. 1991 Nov 14;180(3):1416–1421. doi: 10.1016/s0006-291x(05)81354-3. [DOI] [PubMed] [Google Scholar]
  17. Martino E., Seo H., Lernmark A., Refetoff S. Ontogenetic patterns of thyrotropin-releasing hormone-like material in rat hypothalamus, pancreas, and retina: selective effect of light deprivation. Proc Natl Acad Sci U S A. 1980 Jul;77(7):4345–4348. doi: 10.1073/pnas.77.7.4345. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Samuelsson B. Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. Science. 1983 May 6;220(4597):568–575. doi: 10.1126/science.6301011. [DOI] [PubMed] [Google Scholar]
  19. Samuelsson B. Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. Science. 1983 May 6;220(4597):568–575. doi: 10.1126/science.6301011. [DOI] [PubMed] [Google Scholar]
  20. Serhan C. N., Hamberg M., Samuelsson B. Lipoxins: novel series of biologically active compounds formed from arachidonic acid in human leukocytes. Proc Natl Acad Sci U S A. 1984 Sep;81(17):5335–5339. doi: 10.1073/pnas.81.17.5335. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Serhan C. N., Hamberg M., Samuelsson B., Morris J., Wishka D. G. On the stereochemistry and biosynthesis of lipoxin B. Proc Natl Acad Sci U S A. 1986 Apr;83(7):1983–1987. doi: 10.1073/pnas.83.7.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Serhan C. N., Hamberg M., Samuelsson B. Trihydroxytetraenes: a novel series of compounds formed from arachidonic acid in human leukocytes. Biochem Biophys Res Commun. 1984 Feb 14;118(3):943–949. doi: 10.1016/0006-291x(84)91486-4. [DOI] [PubMed] [Google Scholar]
  23. Serhan C. N., Hirsch U., Palmblad J., Samuelsson B. Formation of lipoxin A by granulocytes from eosinophilic donors. FEBS Lett. 1987 Jun 15;217(2):242–246. doi: 10.1016/0014-5793(87)80671-3. [DOI] [PubMed] [Google Scholar]
  24. Serhan C. N., Nicolaou K. C., Webber S. E., Veale C. A., Dahlén S. E., Puustinen T. J., Samuelsson B. Lipoxin A. Stereochemistry and biosynthesis. J Biol Chem. 1986 Dec 15;261(35):16340–16345. [PubMed] [Google Scholar]
  25. Soyombo O., Spur B. W., Lee T. H. Effects of lipoxin A4 on chemotaxis and degranulation of human eosinophils stimulated by platelet-activating factor and N-formyl-L-methionyl-L-leucyl-L-phenylalanine. Allergy. 1994 Apr;49(4):230–234. doi: 10.1111/j.1398-9995.1994.tb02654.x. [DOI] [PubMed] [Google Scholar]
  26. Taylor G. W., Taylor I., Black P., Maltby N. H., Turner N., Fuller R. W., Dollery C. T. Urinary leukotriene E4 after antigen challenge and in acute asthma and allergic rhinitis. Lancet. 1989 Mar 18;1(8638):584–588. doi: 10.1016/s0140-6736(89)91611-5. [DOI] [PubMed] [Google Scholar]

Articles from Thorax are provided here courtesy of BMJ Publishing Group

RESOURCES