Skip to main content
PMC home page
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1969 Nov;22(6):654–658. doi: 10.1136/jcp.22.6.654

Isolation of a Coxsackie virus group B, type 5, from the heart of a fatal case of myocarditis in an adult

Maurice Longson 1, F M Cole 1,1, Derek Davies 1
PMCID: PMC474338  PMID: 5365336

Abstract

The cause of a fatal case of myocarditis in an adolescent male was established at necropsy by the isolation of Coxsackie virus group B, type 5, from myocardium and bowel. An antibody assay on a single serum is reported. This is believed to be a first report and its significance is assessed.

Full text

PDF
654

Images in this article

656Image
on p.656
656Image
on p.656
656Image
on p.656

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BELL J. F., MEIS A. Pericarditis in infection due to Coxsackie virus group B type 3. N Engl J Med. 1959 Jul 16;261(3):126–128. doi: 10.1056/NEJM195907162610304. [DOI] [PubMed] [Google Scholar]
  2. Bell E. J., Grist N. R. Coxsackie virus infections in patients with acute cardiac disease and chest pain. Scott Med J. 1968 Feb;13(2):47–51. doi: 10.1177/003693306801300204. [DOI] [PubMed] [Google Scholar]
  3. Burch G. E., Sun S. C., Colcolough H. L., Sohal R. S., DePasquale N. P. Coxsackie B viral myocarditis and valvulitis identified in routine autopsy specimens by immunofluorescent techniques. Am Heart J. 1967 Jul;74(1):13–23. doi: 10.1016/0002-8703(67)90035-x. [DOI] [PubMed] [Google Scholar]
  4. COID C. R., TOBIN J. O., BESWICK T. S. The sensitivity of monkeys to subcutaneous inoculation of the Brunenders strain of type-I poliomyelitis virus. J Pathol Bacteriol. 1960 Apr;79:325–330. doi: 10.1002/path.1700790214. [DOI] [PubMed] [Google Scholar]
  5. CONNOLLY J. H. Myocarditis during Coxsackie BS infection. Br Med J. 1961 Mar 25;1(5229):877–878. doi: 10.1136/bmj.1.5229.877. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. COSSART Y. E., BURGES J. A. FATAL COXSACKIE B MYOCARDITIS IN AN ADULT. Med J Aust. 1965 Mar 6;1(10):337–338. doi: 10.5694/j.1326-5377.1965.tb71698.x. [DOI] [PubMed] [Google Scholar]
  7. FLETCHER E., BRENNAN C. F. Cardiac complications of Coxsackie-virus infection. Lancet. 1957 May 4;272(6975):913–915. doi: 10.1016/s0140-6736(57)91229-1. [DOI] [PubMed] [Google Scholar]
  8. Gamba D., Dolivo G., Bozic C. Cas de myocardites virales chez des nouveau-nés. Rev Med Suisse Romande. 1966 Mar;86(3):206–215. [PubMed] [Google Scholar]
  9. HORSTMANN D. M. Acute poliomyelitis relation of physical activity at the time of onset to the course of the disease. J Am Med Assoc. 1950 Jan 28;142(4):236–241. doi: 10.1001/jama.1950.02910220016004. [DOI] [PubMed] [Google Scholar]
  10. Helin M., Savola J., Lapinleimu K. Cardiac manifestations during a Coxsackie B5 epidemic. Br Med J. 1968 Jul 13;3(5610):97–99. doi: 10.1136/bmj.3.5610.97. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. JUNGEBLUT C. W. Newer knowledge on the pathogenesis of poliomyelitis. J Pediatr. 1950 Jul;37(1):109–128. doi: 10.1016/s0022-3476(50)80013-6. [DOI] [PubMed] [Google Scholar]
  12. Jennings R. C. Coxsackie group B fatal neonatal myocarditis associated with cardiomegaly. J Clin Pathol. 1966 Jul;19(4):325–327. doi: 10.1136/jcp.19.4.325. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. KIBRICK S. CURRENT STATUS OF COXSACKIE AND ECHO VIRUSES IN HUMAN DISEASE. Prog Med Virol. 1964;6:27–70. [PubMed] [Google Scholar]
  14. LOU T. Y., WENNER H. A., KAMITSUKA P. S. Experimental infections with Coxackie viruses. II. Myocarditis in Cynomolgus monkeys infected with B 4 virus. Arch Gesamte Virusforsch. 1961;10:451–464. [PubMed] [Google Scholar]
  15. Longson M. Coxsackie virus heart diseases. Br Med J. 1968 Aug 31;3(5617):555–556. doi: 10.1136/bmj.3.5617.555-b. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. MONTGOMERY J., GEAR J., PRINSLOO F. R., KAHN M., KIRSCH Z. G. Myocarditis of the newborn; an outbreak in a maternity home in Southern Rhodesia associated with Coxsackie group-B virus infection. S Afr Med J. 1955 Jun 25;29(26):608–612. [PubMed] [Google Scholar]
  17. NULL F. C., Jr, CASTLE C. H. Adultpericarditis and myocarditis due to Coxsackie virus group B, type 5. N Engl J Med. 1959 Nov 5;261:937–942. doi: 10.1056/NEJM195911052611903. [DOI] [PubMed] [Google Scholar]
  18. RABIN E. R., HASSAN S. A., JENSON A. B., MELNICK J. L. COXSACKIE VIRUS B3 MYOCARDITIS IN MICE. AN ELECTRON MICROSCOPIC, IMMUNOFLUORESCENT AND VIRUS-ASSAY STUDY. Am J Pathol. 1964 May;44:775–797. [PMC free article] [PubMed] [Google Scholar]
  19. SANYAL S. K., MAHDAVY M., GABRIELSON M. O., VIDONE R. A., BROWNE M. J. FATAL MYOCARDITIS IN AN ADOLESCENT CAUSED BY COXSACKIE VIRUS, GROUP B, TYPE FOUR. Pediatrics. 1965 Jan;35:36–41. [PubMed] [Google Scholar]
  20. Sainani G. S., Krompotic E., Slodki S. J. Adult heart disease due to the Coxsackie virus B infection. Medicine (Baltimore) 1968 Mar;47(2):133–147. doi: 10.1097/00005792-196803000-00003. [DOI] [PubMed] [Google Scholar]
  21. Smith W. G. Adult heart disease due to the Coxsackie virus group B. Br Heart J. 1966 Mar;28(2):204–220. doi: 10.1136/hrt.28.2.204. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Spirito L., Braito A. Réinfection herpètique du type éclatant exceptionnelment diffuse au cours du traitement cortisonique de la méningite méningococcique. G Mal Infett Parassit. 1966 Nov;18(11):763–764. [PubMed] [Google Scholar]
  23. Sun N. C., Smith V. M. Hepatitis associated with myocarditis. Unusual manifestation of infection with Coxsackie virus group B, type 3. N Engl J Med. 1966 Jan 27;274(4):190–193. doi: 10.1056/NEJM196601272740405. [DOI] [PubMed] [Google Scholar]
  24. TILLES J. G., ELSON S. H., SHAKA J. A., ABELMANN W. H., LERNER A. M., FINLAND M. EFFECTS OF EXERCISE ON COXSACKIE A9 MYOCARDITIS IN ADULT MICE. Proc Soc Exp Biol Med. 1964 Dec;117:777–782. doi: 10.3181/00379727-117-29696. [DOI] [PubMed] [Google Scholar]
  25. WOODWARD T. E., McCRUMB F. R., Jr, CAREY T. N., TOGO Y. Viral and rickettsial causes of cardiac disease, including the Coxsackie virus etiology of pericarditis and myocarditis. Ann Intern Med. 1960 Dec 15;53:1130–1150. doi: 10.7326/0003-4819-53-6-1130. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES