Abstract
Argentaffin carcinoma (carcinoid tumour) of the ileum has been found to be associated with ischaemic ileal necrosis due to elastic sclerosis of the mesenteric blood vessels. This vascular change was present in 17 out of 25 ileal tumours, all of them invasive, but was absent in 75 appendicular, rectal, and other carcinoids. The pathology is described and essential points of difference are noted from the cardiovascular changes in the carcinoid syndrome. This elastic vascular sclerosis may be due to a product of the tumour and constitute an additional component of the complex range of changes that makes up `the carcinoid spectrum'.
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- Anthony P. P. Gangrene of the small intestine--a complication of argentaffin carcinoma. Br J Surg. 1970 Feb;57(2):118–122. doi: 10.1002/bjs.1800570209. [DOI] [PubMed] [Google Scholar]
- DOCKERTY M. B. CARCINOID TUMORS. Calif Med. 1963 Sep;99:157–160. [PMC free article] [PubMed] [Google Scholar]
- GILLMAN T., PENN J., BRONKS D., ROUX M. Abnormal elastic fibers; appearance in cutaneous carcinoma, irradiation injuries, and arterial and other degenerative connective tissue lesions in man. AMA Arch Pathol. 1955 Jun;59(6):733–749. [PubMed] [Google Scholar]
- HADDY F. J. Serotonin and the vascular system. Angiology. 1960 Feb;11:21–24. doi: 10.1177/000331976001100104. [DOI] [PubMed] [Google Scholar]
- HOLDSTOCK D. J., MATHIAS A. P., SCHACHTER M. A comparative study of kinin, kallidin, and bradykinin. Br J Pharmacol Chemother. 1957 Jun;12(2):149–158. doi: 10.1111/j.1476-5381.1957.tb00113.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
- KOWLESSAR O. D., LAW D. H., SLEISENGER M. H. Malabsorption syndrome associated with metastatic carcinoid tumor. Am J Med. 1959 Oct;27:673–677. doi: 10.1016/0002-9343(59)90051-8. [DOI] [PubMed] [Google Scholar]
- MACDONALD R. A., ROBBINS S. L., MALLORY G. K. Morphologic effects of serotonin (5-hydroxytryptamine). AMA Arch Pathol. 1958 Apr;65(4):369–377. [PubMed] [Google Scholar]
- MOERTEL C. G., SAUER W. G., DOCKERTY M. B., BAGGENSTOSS A. H. Life history of the carcinoid tumor of the small intestine. Cancer. 1961 Sep-Oct;14:901–912. doi: 10.1002/1097-0142(196109/10)14:5<901::aid-cncr2820140502>3.0.co;2-q. [DOI] [PubMed] [Google Scholar]
- Mackenzie D. H., Wilson J. F., Cooke K. B. Elastofibroma. J Clin Pathol. 1968 Jul;21(4):470–475. doi: 10.1136/jcp.21.4.470. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Marston A., Pheils M. T., Thomas M. L., Morson B. C. Ischaemic colitis. Gut. 1966 Feb;7(1):1–15. doi: 10.1136/gut.7.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McKinney B., Crawford M. A. Fibrosis in guineapig heart produced by plantain diet. Lancet. 1965 Oct 30;2(7418):880–882. doi: 10.1016/s0140-6736(65)92506-7. [DOI] [PubMed] [Google Scholar]
- OATES J. A., MELMON K., SJOERDSMA A., GILLESPIE L., MASON D. T. RELEASE OF A KININ PEPTIDE IN THE CARCINOID SYNDROME. Lancet. 1964 Mar 7;1(7332):514–517. doi: 10.1016/s0140-6736(64)92907-1. [DOI] [PubMed] [Google Scholar]
- ROBERTS W. C., SJOERDSMA A. THE CARDIAC DISEASE ASSOCIATED WITH THE CARCINOID SYNDROME (CARCINOID HEART DISEASE). Am J Med. 1964 Jan;36:5–34. doi: 10.1016/0002-9343(64)90145-7. [DOI] [PubMed] [Google Scholar]
- Sandler M., Karim S. M., Williams E. D. Prostaglandins in amine-peptide-secreting tumours. Lancet. 1968 Nov 16;2(7577):1053–1054. doi: 10.1016/s0140-6736(68)91528-6. [DOI] [PubMed] [Google Scholar]
- TEDESCHI C. G., BOTTA G. C. Retractile mesenteritis. N Engl J Med. 1962 May 17;266:1035–1040. doi: 10.1056/NEJM196205172662005. [DOI] [PubMed] [Google Scholar]
- WILLIAMS E. D., SANDLER M. The classification of carcinoid tum ours. Lancet. 1963 Feb 2;1(7275):238–239. doi: 10.1016/s0140-6736(63)90951-6. [DOI] [PubMed] [Google Scholar]
- WOLFE H. R., DAVIES A., MATHIAS A. P., SCHACHTER M. Metastatic argentaffinoma secreting 5-hydroxytryptamine in a patient with a patent foramen ovale. Br Med J. 1960 Mar 26;1(5177):925–929. doi: 10.1136/bmj.1.5177.925. [DOI] [PMC free article] [PubMed] [Google Scholar]