Skip to main content
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1974 Dec;27(12):963–966. doi: 10.1136/jcp.27.12.963

Nodular, non-cirrhotic liver associated with portal hypertension in a patient with rheumatoid arthritis

M Harris 1,2,3, R M Rash 1,2,3, I W Dymock 1,2,3
PMCID: PMC475564  PMID: 4452745

Abstract

A patient with rheumatoid arthritis developed portal hypertension and died from bleeding oesophageal varices. The liver was small and showed a nodular, non-cirrhotic pattern similar to that described by Blendis et al (1970 and 1974) in association with Felty's syndrome. This appears to be the first report of a patient with this liver lesion associated with rheumatoid arthritis in the absence of Felty's syndrome. The liver lesions described here are compared with partial nodular transformation and nodular regenerative hyperplasia; in spite of some differences it is not proven that these are distinct entities and further study is required to settle this question.

Full text

PDF
963

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BYWATERS E. G. Peripheral vascular obstruction in rheumatoid arthritis and its relationship to other vascular lesions. Ann Rheum Dis. 1957 Mar;16(1):84–103. doi: 10.1136/ard.16.1.84. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Blendis L. M., Ansell I. D., Jones K. L., Hamilton E., Williams R. Liver in Felty's syndrome. Br Med J. 1970 Jan 17;1(5689):131–135. doi: 10.1136/bmj.1.5689.131. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Blendis L. M., Parkinson M. C., Shilkin K. B., Williams R. Nodular regenerative hyperplasia of the liver in Felty's syndrome. Q J Med. 1974 Jan;43(169):25–32. [PubMed] [Google Scholar]
  4. STEINER P. E. Nodular regenerative hyperplasia of the liver. Am J Pathol. 1959 Sep-Oct;35:943–953. [PMC free article] [PubMed] [Google Scholar]
  5. Sherlock S., Feldman C. A., Moran B., Scheuer P. J. Partial nodular transformation of the liver with portal hypertension. Am J Med. 1966 Feb;40(2):195–203. doi: 10.1016/0002-9343(66)90100-8. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES