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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1977 Jun;30(6):563–568. doi: 10.1136/jcp.30.6.563

Macrophage infiltration of breast tumours: a prospective study.

I Lauder, W Aherne, J Stewart, R Sainsbury
PMCID: PMC476469  PMID: 874114

Abstract

In 50 cases of infiltrating breast cancer investigated in a prospective study the number of macrophages within each tumour was assessed. The macrophages were identified by their cytoplasmic acid phosphatase activity. The number of lymphocytes and plasma cells within the tumours were graded by a scoring technique. Significantly fewer cases with metastases were found among those with high macrophage and plasma cell scores. There was no correlation between lymphoreticular infiltration and the degree of tumour differentiation, but in cases without metastases the lymphoreticular infiltration between tumour cells was nearly always only slight when the macrophage score was low.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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