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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1978 Jan;31(1):89–92. doi: 10.1136/jcp.31.1.89

Dysfibrinogenaemia and liver cell growth.

R D Barr, M Allardyce, P W Brunt, J L McPhie
PMCID: PMC476725  PMID: 627621

Abstract

From the evidence presented, it is proposed that 'dysfibrinogenaemia' represents the production of normal fetal fibrinogen by rapidly proliferating liver cells in both regenerating and neoplastic tissue. Prolongation of the reptilase clotting time, which was formerly believed to reflect dysfibrinogenaemia, may be rather the result of hepatocytic death.

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Selected References

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