Abstract
The present study was designed to compare the Thyopac and Triosorb triiodothyronine uptake tests. A normal range was established for the two procedures. Neither test was affected by iodine-containing drugs or contrast media but abnormal results were obtained during pregnancy and in subjects receiving oestrogens. Both tests proved satisfactory in the diagnosis of hypo- and hyperthyroidism, giving results consistent with clinical assessment and with serum protein-bound iodine determinations. The Thyopac procedure was preferred for a number of reasons. It requires less plasma; it is slightly simpler and quicker and it is not time dependent.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- CLARK F., HORN D. B. ASSESSMENT OF THYROID FUNCTION BY THE COMBINED USE OF THE SERUM PROTEIN-BOUND IODINE AND RESIN UPTAKE OF 131-I-TRIIODOTHYRONINE. J Clin Endocrinol Metab. 1965 Jan;25:39–45. doi: 10.1210/jcem-25-1-39. [DOI] [PubMed] [Google Scholar]
- Clark F., Brown H. J. Evaluation of Thyopac-3 test in the in-vitro assessment of thyroid function. Br Med J. 1970 Mar 21;1(5698):713–715. doi: 10.1136/bmj.1.5698.713. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Clark F., Brown H. J. Free thyroxine index. Br Med J. 1970 May 30;2(5708):543–543. doi: 10.1136/bmj.2.5708.543-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Goolden A. W., Gartside J. M., Sanderson C. Thyroid status in pregnancy and in women taking oral contraceptives. Lancet. 1967 Jan 7;1(7480):12–15. doi: 10.1016/s0140-6736(67)92420-8. [DOI] [PubMed] [Google Scholar]
- Howorth P. J., Maclagan N. F. Clinical application of serum-total-thyroxine estimation, resin uptake, and free-thyroxine index. Lancet. 1969 Feb 1;1(7588):224–228. doi: 10.1016/s0140-6736(69)91240-9. [DOI] [PubMed] [Google Scholar]
- MITCHELL M. L., HARDEN A. B., O'ROURKE M. E. The in vitro resin sponge uptake of triiodothyronine-I-131 from serum in thyroid disease and in pregnancy. J Clin Endocrinol Metab. 1960 Nov;20:1474–1483. doi: 10.1210/jcem-20-11-1474. [DOI] [PubMed] [Google Scholar]