Abstract
The Ziehl-Neelsen stain is compared with three alternative methods of staining tubercle bacilli in paraffin sections: Fite's method (1938); a modification by Armstrong and Price (1947) of Fite's method; and a fluorescent method using the auramine-phenol stain.
The fluorescent method was found to be the most effective of the four methods and its use is recommended as a routine tool in diagnostic histopathology.
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- ARMSTRONG A. R., PRICE N. E. Acid-fast bacilli in paraffin sections of tuberculous tissue. Can Med Assoc J. 1947 Jan;56(1):83–83. [PMC free article] [PubMed] [Google Scholar]
- Fite G. L. The staining of acid-fast bacilli in paraffin sections. Am J Pathol. 1938 Jul;14(4):491–507. [PMC free article] [PubMed] [Google Scholar]
- KOCH M. L., COTE R. A. COMPARISON OF FLUORESCENCE MICROSCOPY WITH ZIEHL-NEELSEN STAIN FOR DEMONSTRATION OF ACID-FAST BACILLI IN SMEAR PREPARATIONS AND TISSUE SECTIONS. Am Rev Respir Dis. 1965 Feb;91:283–284. doi: 10.1164/arrd.1965.91.2.283. [DOI] [PubMed] [Google Scholar]
- Mansfield R. E. An improved method for the fluorochrome staining of mycobacteria in tissues and smears. Am J Clin Pathol. 1970 Mar;53(3):394–406. doi: 10.1093/ajcp/53.3.394. [DOI] [PubMed] [Google Scholar]
- Wang W. L. Contamination of tissue sections with acid-fast bacilli as detected by fluorescence microscopy. Am J Clin Pathol. 1969 Jan;51(1):71–75. doi: 10.1093/ajcp/51.1.71. [DOI] [PubMed] [Google Scholar]