Abstract
Estimations of red cell and blood volumes using 51Cr were carried out on a group of 37 people over the age of 70 who were not anaemic. Subjects with clinical conditions known to affect red cell production were excluded. The mean values for red cell and blood volumes were found to be comparable with those of a control group of young adults. Seven people had red cell volumes below the accepted range in young adults but no reason was found for this difference.
Red cell survival was determined concurrently on 11 of the group and did not differ from those of young controls.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- CHAPLIN H., Jr, MOLLISON P. L. Correction for plasma trapped in the red cell column of the hematocrit. Blood. 1952 Dec;7(12):1227–1238. [PubMed] [Google Scholar]
- CRAWFORD H., DE GRUCHY G. C. The use of radioactive chromium (51Cr) in clinical medicine. Med J Aust. 1958 May 17;45(20):657–662. doi: 10.5694/j.1326-5377.1958.tb86668.x. [DOI] [PubMed] [Google Scholar]
- DONOHUE D. M., MOTULSKY A. G., GIBLETT E. R., PIRZIO-BIROLI G., VIRANUVATTI V., FINCH C. A. The use of chromium as red-cell tag. Br J Haematol. 1955 Jul;1(3):249–263. doi: 10.1111/j.1365-2141.1955.tb05508.x. [DOI] [PubMed] [Google Scholar]
- EDWARDS K. D., WHYTE H. M. The relation of blood volume to body composition. Clin Sci. 1960 Aug;19:399–405. [PubMed] [Google Scholar]
- MOLLISON P. L., VEALL N. The use of the isotope 51Cr as a label for red cells. Br J Haematol. 1955 Jan;1(1):62–74. doi: 10.1111/j.1365-2141.1955.tb05489.x. [DOI] [PubMed] [Google Scholar]
- READ R. C., WILSON G. W., GARDNER F. H. The use of radioactive sodium chromate to evaluate the life span of the red blood cell in health and certain hematologic disorders. Am J Med Sci. 1954 Jul;228(1):40–52. doi: 10.1097/00000441-195407000-00005. [DOI] [PubMed] [Google Scholar]
- REMINGTON J. W., BAKER C. H. Evaluation of blood volume measurement techniques. Circ Res. 1961 Jan;9:60–68. doi: 10.1161/01.res.9.1.60. [DOI] [PubMed] [Google Scholar]
- SKLAROFF D. M. Isotopic determination of blood volume in the normal aged. Am J Roentgenol Radium Ther Nucl Med. 1956 Jun;75(6):1082–1083. [PubMed] [Google Scholar]
- SMITH R. H. Normal blood volumes in men and women over sixty years of age as determined by a modified Cr51 method. Anesthesiology. 1958 Nov-Dec;19(6):752–756. doi: 10.1097/00000542-195811000-00006. [DOI] [PubMed] [Google Scholar]