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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1962 Jul;15(4):380–382. doi: 10.1136/jcp.15.4.380

A study in isolating circulating cancer cells from blood

B V Nabar 1
PMCID: PMC480417  PMID: 14477757

Abstract

Samples of blood from 49 cancer cases were examined for free cancer cells. Cells identified as cancer cells were found in the blood of four. Cells which looked highly suspicious of being cancer cells were isolated from the blood of nine other cases. No conclusion was possible regarding the type of cells in eight cases. This illustrates the difficulty of cytological diagnosis and shows the need for new methods of identification.

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Selected References

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  1. ALEXANDER R. F., SPRIGGS A. I. The differential diagnosis of tumour cells in circulating blood. J Clin Pathol. 1960 Sep;13:414–424. doi: 10.1136/jcp.13.5.414. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. LONG L., JONASSON O., ROBERTS S., MCGRATH R., MCGREW E., COLE W. H. Cancer cells in blood. Results of a simplified isolation technique. Arch Surg. 1960 Jun;80:910–919. doi: 10.1001/archsurg.1960.01290230028004. [DOI] [PubMed] [Google Scholar]
  3. SANDBERG A. A., MOORE G. E., SCHUBARG J. R. Atypical cells in the blood of cancer patients; differentiation from tumor cells. J Natl Cancer Inst. 1959 Mar;22(3):555–565. [PubMed] [Google Scholar]
  4. SEAL S. H. Silicone flotation: a simple quantitative method for the isolation of free-floating cancer cells from the blood. Cancer. 1959 May-Jun;12(3):590–595. doi: 10.1002/1097-0142(195905/06)12:3<590::aid-cncr2820120318>3.0.co;2-n. [DOI] [PubMed] [Google Scholar]

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