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. 1979 Nov;42(5):553–561. doi: 10.1136/hrt.42.5.553

Thallium-201 imaging in assessment of aortocoronary artery bypass graft patency.

J A Sbarbaro, H Karunaratne, S Cantez, P V Harper, L Resnekov
PMCID: PMC482199  PMID: 316333

Abstract

Fifteen patients with significant coronary artery disease confirmed by cardiac catheterisation were studied before and after aortocoronary artery bypass graft surgery by rest and exercise 201Tl myocardial scintigraphy in an attempt to predict graft status non-invasively. Segmental myocardial perfusion comparisons in pre- and postoperative exercise images allowed correct predictions of high (greater than or equal to 67%) or low (less than or equal to 50%) graft patency rates in 10 of 15 patients, while similar comparisons in postoperative rest and exercise images yielded 13 of 15 correct predictions. Furthermore, 20 of 21 myocardial segments with increased postoperative perfusion when compared with corresponding segments in preoperative exercise studies were supplied by patent grafts. Regional graft occlusion, however, was difficult to predict. It was also difficult to predict graft status when myocardial segments were shown to have unchanged perfusion postoperatively as compared with the preoperative segmental assessment. Despite these limitations, the non-invasive technique of 201Tl imaging can provide useful information regarding coronary artery bypass graft patency.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bailey I. K., Griffith L. S., Rouleau J., Strauss W., Pitt B. Thallium-201 myocardial perfusion imaging at rest and during exercise. Comparative sensitivity to electrocardiography in coronary artery disease. Circulation. 1977 Jan;55(1):79–87. doi: 10.1161/01.cir.55.1.79. [DOI] [PubMed] [Google Scholar]
  2. Botvinick E. H., Taradash M. R., Shames D. M., Parmley W. W. Thallium-20 1 myocardial perfusion scintigraphy for the clinical clarification of normal, abnormal and equivocal electrocardiographic stress tests. Am J Cardiol. 1978 Jan;41(1):43–51. doi: 10.1016/0002-9149(78)90130-3. [DOI] [PubMed] [Google Scholar]
  3. Bradley-Moore P. R., Lebowitz E., Greene M. W., Atkins H. L., Ansari A. N. Thallium-201 for medical use. II: Biologic behavior. J Nucl Med. 1975 Feb;16(2):156–160. [PubMed] [Google Scholar]
  4. Braunwald E. Coronary-artery surgery at the crossroads. N Engl J Med. 1977 Sep 22;297(12):661–663. doi: 10.1056/NEJM197709222971209. [DOI] [PubMed] [Google Scholar]
  5. Bruce R. A., Kusumi F., Hosmer D. Maximal oxygen intake and nomographic assessment of functional aerobic impairment in cardiovascular disease. Am Heart J. 1973 Apr;85(4):546–562. doi: 10.1016/0002-8703(73)90502-4. [DOI] [PubMed] [Google Scholar]
  6. Bulkely B. H., Hutchins G. M. Myocardial consequences of coronary artery bypass graft surgery. The paradox of necrosis in areas of revascularization. Circulation. 1977 Dec;56(6):906–913. doi: 10.1161/01.cir.56.6.906. [DOI] [PubMed] [Google Scholar]
  7. Greenberg B. H., Hart R., Botvinick E. H., Werner J. A., Brundage B. H., Shames D. M., Chatterjee K., Parmley W. W. Thallium-201 myocardial perfusion scintigraphy to evaluate patients after coronary bypass surgery. Am J Cardiol. 1978 Aug;42(2):167–176. doi: 10.1016/0002-9149(78)90896-2. [DOI] [PubMed] [Google Scholar]
  8. Judkins M. P. Selective coronary arteriography. I. A percutaneous transfemoral technic. Radiology. 1967 Nov;89(5):815–824. doi: 10.1148/89.5.815. [DOI] [PubMed] [Google Scholar]
  9. Lebowitz E., Greene M. W., Fairchild R., Bradley-Moore P. R., Atkins H. L., Ansari A. N., Richards P., Belgrave E. Thallium-201 for medical use. I. J Nucl Med. 1975 Feb;16(2):151–155. [PubMed] [Google Scholar]
  10. Lebowitz E., Greene M. W., Fairchild R., Bradley-Moore P. R., Atkins H. L., Ansari A. N., Richards P., Belgrave E. Thallium-201 for medical use. I. J Nucl Med. 1975 Feb;16(2):151–155. [PubMed] [Google Scholar]
  11. Lebowitz E., Greene M. W., Fairchild R., Bradley-Moore P. R., Atkins H. L., Ansari A. N., Richards P., Belgrave E. Thallium-201 for medical use. I. J Nucl Med. 1975 Feb;16(2):151–155. [PubMed] [Google Scholar]
  12. McIntosh H. D., Garcia J. A. The first decade of aortocoronary bypass grafting, 1967-1977. A review. Circulation. 1978 Mar;57(3):405–431. doi: 10.1161/01.cir.57.3.405. [DOI] [PubMed] [Google Scholar]
  13. Mueller T. M., Marcus M. L., Ehrhardt J. C., Chaudhuri T., Abboud F. M. Limitations of thallium-201 myocardial perfusion scintigrams. Circulation. 1976 Oct;54(4):640–646. doi: 10.1161/01.cir.54.4.640. [DOI] [PubMed] [Google Scholar]
  14. Murphy M. L., Hultgren H. N., Detre K., Thomsen J., Takaro T. Treatment of chronic stable angina. A preliminary report of survival data of the randomized Veterans Administration cooperative study. N Engl J Med. 1977 Sep 22;297(12):621–627. doi: 10.1056/NEJM197709222971201. [DOI] [PubMed] [Google Scholar]
  15. Murphy M. L., Hultgren H. N., Detre K., Thomsen J., Takaro T. Treatment of chronic stable angina. A preliminary report of survival data of the randomized Veterans Administration cooperative study. N Engl J Med. 1977 Sep 22;297(12):621–627. doi: 10.1056/NEJM197709222971201. [DOI] [PubMed] [Google Scholar]
  16. Pohost G. M., Zir L. M., Moore R. H., McKusick K. A., Guiney T. E., Beller G. A. Differentiation of transiently ischemic from infarcted myocardium by serial imaging after a single dose of thallium-201. Circulation. 1977 Feb;55(2):294–302. doi: 10.1161/01.cir.55.2.294. [DOI] [PubMed] [Google Scholar]
  17. Ritchie J. L., Narahara K. A., Trobaugh G. B., Williams D. L., Hamilton G. W. Thallium-201 myocardial imaging before and after coronary revascularization: assessment of regional myocardial blood flow and graft patency. Circulation. 1977 Nov;56(5):830–836. doi: 10.1161/01.cir.56.5.830. [DOI] [PubMed] [Google Scholar]
  18. Ritchie J. L., Trobaugh G. B., Hamilton G. W., Gould K. L., Narahara K. A., Murray J. A., Williams D. L. Myocardial imaging with thallium-201 at rest and during exercise. Comparison with coronary arteriography and resting and stress electrocardiography. Circulation. 1977 Jul;56(1):66–71. doi: 10.1161/01.cir.56.1.66. [DOI] [PubMed] [Google Scholar]
  19. Strauss H. W., Harrison K., Langan J. K., Lebowitz E., Pitt B. Thallium-201 for myocardial imaging. Relation of thallium-201 to regional myocardial perfusion. Circulation. 1975 Apr;51(4):641–645. doi: 10.1161/01.cir.51.4.641. [DOI] [PubMed] [Google Scholar]
  20. Strauss H. W., Pitt B. Thallium-201 as a myocardial imaging agent. Semin Nucl Med. 1977 Jan;7(1):49–58. doi: 10.1016/s0001-2998(77)80007-x. [DOI] [PubMed] [Google Scholar]
  21. Walsh W. F., Karunaratne H. B., Resnekov L., Fill H. R., Harper P. V. Assessment of diagnostic value of technetium-99m pyrophosphate myocardial scintigraphy in 80 patients with possible acute myocardial infarction. Br Heart J. 1977 Sep;39(9):974–981. doi: 10.1136/hrt.39.9.974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Weich H. F., Strauss H. W., Pitt B. The extraction of thallium-201 by the myocardium. Circulation. 1977 Aug;56(2):188–191. doi: 10.1161/01.cir.56.2.188. [DOI] [PubMed] [Google Scholar]
  23. Zaret B. L., Martin N. D., McGowan R. L., Strauss H. W., Wells H. P., Jr, Flamm M. D., Jr Rest and exercise potassium-43 myocardial perfusion imaging for the noninvasive evaluation of aortocoronary bypass surgery. Circulation. 1974 Apr;49(4):688–695. doi: 10.1161/01.cir.49.4.688. [DOI] [PubMed] [Google Scholar]

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