Skip to main content
NCBI home page
British Heart Journal logoLink to British Heart Journal
. 1981 Nov;46(5):539–544. doi: 10.1136/hrt.46.5.539

Prophylactic antibiotics for cardiac pacemaker implantation. A prospective trail.

M F Muers, A G Arnold, P Sleight
PMCID: PMC482693  PMID: 7317219

Abstract

A prospective trial was conducted to assess the value of prophylactic antibiotic treatment in preventing postoperative infection of permanent transvenous pacemaker systems. Four hundred and thirty-one patients were randomly allocated to treatment (234) or no-treatment (197) groups. Treated patients received systemic benzylpenicillin and flucloxacillin just before operation and one and six hours afterwards. Nine primary generator pocket infections occurred without evidence of wound dehiscence or skin erosion. Seven infections were in untreated patients and two in treated patients. Antibiotic prophylaxis diminishes the risk of infection after pacemaker implantations.

Full text

PDF
539

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Arnold A. G. Predictive value of ST segment elevation in cardiac pacing. Br Heart J. 1980 Oct;44(4):416–418. doi: 10.1136/hrt.44.4.416. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Burke J. F. The effective period of preventive antibiotic action in experimental incisions and dermal lesions. Surgery. 1961 Jul;50:161–168. [PubMed] [Google Scholar]
  3. Codini M. A., Caralis D. G., Voigt G. C. Permanent ventricular pacing: a ten year experience. Complications of implantation, incidence of congestive heart failure and coronary artery disease. Johns Hopkins Med J. 1974 Feb;134(2):118–127. [PubMed] [Google Scholar]
  4. Coles D. M., Hunyor S. N., Jones D., Cartmill T. B. Australian pacemakers: a follow-up survey. Med J Aust. 1975 Oct 25;2(17):666–668. [PubMed] [Google Scholar]
  5. Conklin E. F., Giannelli S., Jr, Nealon T. F., Jr Four hundred consecutive patients with permanent transvenous pacemakers. J Thorac Cardiovasc Surg. 1975 Jan;69(1):1–7. [PubMed] [Google Scholar]
  6. Firor W. B., Lopez J. F., Nanson E. M., Mori M. Clinical management of the infected pacemaker. Ann Thorac Surg. 1968 Nov;6(5):431–436. doi: 10.1016/s0003-4975(10)66049-3. [DOI] [PubMed] [Google Scholar]
  7. Golden G. T., Lovett W. L., Harrah J. D., Wellons H. A., Jr, Nolan S. P. The treatment of extruded and infected permanent cardiac pulse generators: application of a technique of closed irrigation. Surgery. 1973 Oct;74(4):575–579. [PubMed] [Google Scholar]
  8. Grogler F. M., Frank G., Greven G., Dragojevic D., Oelert H., Leitz K., Dalichau H., Brinke U., Lohlein D., Rogge D. Complications of permanent transvenous cardiac pacing. J Thorac Cardiovasc Surg. 1975 Jun;69(6):895–904. [PubMed] [Google Scholar]
  9. Grover F. L., O'Sullivan M. J., Fosburg R. G. Demand or fixed-rate pacemakers? Eleven-year experience with 76 patients. J Thorac Cardiovasc Surg. 1974 Jan;67(1):142–147. [PubMed] [Google Scholar]
  10. Hartstein A. I., Jackson J., Gilbert D. N. Prophylactic antibiotics and the insertion of permanent transvenous cardiac pacemakers. J Thorac Cardiovasc Surg. 1978 Feb;75(2):219–223. [PubMed] [Google Scholar]
  11. Havia T., Arstila M., Wendelin H., Heinonen R. Permanent endocardial pacing. An analysis of 90 patients. Acta Med Scand Suppl. 1976;596:7–11. [PubMed] [Google Scholar]
  12. Jara F. M., Toledo-Pereyra L., Lewis J. W., Jr, Magilligan D. J., Jr The infected pacemaker pocket. J Thorac Cardiovasc Surg. 1979 Aug;78(2):298–300. [PubMed] [Google Scholar]
  13. Kennelly B. M., Piller L. W. Management of infected transvenous permanent pacemakers. Br Heart J. 1974 Nov;36(11):1133–1140. doi: 10.1136/hrt.36.11.1133. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Lemire G. G., Morin J. E., Dobell A. R. Pacemaker infections: a 12-year review. Can J Surg. 1975 Mar;18(2):181–184. [PubMed] [Google Scholar]
  15. Linschoten H., Meijne N. G., Mellink H. M., Overdijk A. D. Pacemaker implantation and infection. J Cardiovasc Surg (Torino) 1973 Mar-Apr;14(2):126–130. [PubMed] [Google Scholar]
  16. McDonald A., Layton C. Four years experience of cardiac pacemaking with the Devices asynchronous generator. Br Heart J. 1973 Oct;35(10):1041–1046. doi: 10.1136/hrt.35.10.1041. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. McNeill G. P., Taylor N. C. Use of subclavian vein for permanent cardiac pacing. Br Heart J. 1978 Feb;40(2):114–116. doi: 10.1136/hrt.40.2.114. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Pollard J. P., Hughes S. P., Scott J. E., Evans M. J., Benson M. K. Antibiotic prophylaxis in total hip replacement. Br Med J. 1979 Mar 17;1(6165):707–709. doi: 10.1136/bmj.1.6165.707. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Rettig G., Doenecke P., Sen S., Volkmer I., Bette L. Complications with retained transvenous pacemaker electrodes. Am Heart J. 1979 Nov;98(5):587–594. doi: 10.1016/0002-8703(79)90284-9. [DOI] [PubMed] [Google Scholar]
  20. Richardson R. L., Jr, Pate J. W. Prevention of infection of pacemaker pocket. JAMA. 1973 Sep 10;225(11):1388–1388. [PubMed] [Google Scholar]
  21. Siddons H., Nowak K. Surgical complications of implanting pacemakers. Br J Surg. 1975 Dec;62(12):929–935. doi: 10.1002/bjs.1800621202. [DOI] [PubMed] [Google Scholar]
  22. Sloman G., Mond H. G., Ramshaw J., Smith D., Twentyman R. Australia and New Zealand pacemaker survey, 1972. Med J Aust. 1974 Jun 8;1(23):920–923. [PubMed] [Google Scholar]
  23. Sowton E., Hendrix G., Roy P. Ten-year survey of treatment with implanted cardiac pacemaker. Br Med J. 1974 Jul 20;3(5924):155–160. doi: 10.1136/bmj.3.5924.155. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Sprenger K. Ursachen der Elektrodendislokation bei der transvenösen Schrittmacherimplantation. Dtsch Med Wochenschr. 1976 Apr;101(14):537–540. doi: 10.1055/s-0028-1104111. [DOI] [PubMed] [Google Scholar]
  25. Todd R. C., Lightowler C. D., Harris J. Total hip replacement in osteoarthrosis using the Charnley prosthesis. Br Med J. 1972 Jun 24;2(5816):752–755. doi: 10.1136/bmj.2.5816.752. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from British Heart Journal are provided here courtesy of BMJ Publishing Group

RESOURCES