Abstract
Inappropriate percutaneous transluminal coronary angioplasty of the anterior descending artery was avoided in a 52-year-old woman when the intracoronary administration of glyceryl trinitrate immediately before the angioplasty disclosed the organic component of the supposedly fixed, critical (80%) stenosis to be less than 50% of the lumen diameter. The spastic component of the stenosis had not been unmasked by the sublingual administration of two 0.4 mg tablets of glyceryl trinitrate during diagnostic angiography two weeks earlier. Intracoronary glyceryl trinitrate is indicated when suspected coronary spasm persists after the sublingual administration of this drug in potential candidates for percutaneous transluminal coronary angioplasty or coronary bypass surgery.
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- Feldman R. L., Pepine C. J., Curry R. C., Jr, Conti C. R. Coronary arterial responses to graded doses of nitroglycerin. Am J Cardiol. 1979 Jan;43(1):91–97. doi: 10.1016/0002-9149(79)90050-x. [DOI] [PubMed] [Google Scholar]
- Grüntzig A. R., Senning A., Siegenthaler W. E. Nonoperative dilatation of coronary-artery stenosis: percutaneous transluminal coronary angioplasty. N Engl J Med. 1979 Jul 12;301(2):61–68. doi: 10.1056/NEJM197907123010201. [DOI] [PubMed] [Google Scholar]
- Hillis L. D., Braunwald E. Coronary-artery spasm. N Engl J Med. 1978 Sep 28;299(13):695–702. doi: 10.1056/NEJM197809282991305. [DOI] [PubMed] [Google Scholar]
- Kreulen T. H., Kirk E. S., Gorlin R., Cohn L. H., Collins J. J., Jr Coronary artery bypass surgery: assessment of revascularization by determination of blood flow and myocardial mass. Am J Cardiol. 1974 Aug;34(2):129–135. doi: 10.1016/0002-9149(74)90190-8. [DOI] [PubMed] [Google Scholar]
- Wei J. Y., Reid P. R. Quantitative determination of trinitroglycerin in human plasma. Circulation. 1979 Mar;59(3):588–592. doi: 10.1161/01.cir.59.3.588. [DOI] [PubMed] [Google Scholar]
- Wiener L., Kasparian H., Duca P. R., Walinsky P., Gottlieb R. S., Hanckel F., Brest A. N. Spectrum of coronary arterial spasm. Clinical, angiographic and myocardial metabolic experience in 29 cases. Am J Cardiol. 1976 Dec;38(7):945–955. doi: 10.1016/0002-9149(76)90808-0. [DOI] [PubMed] [Google Scholar]
- Yasue H., Omote S., Takizawa A., Nagao M., Miwa K., Tanaka S. Circadian variation of exercise capacity in patients with Prinzmetal's variant angina: role of exercise-induced coronary arterial spasm. Circulation. 1979 May;59(5):938–948. doi: 10.1161/01.cir.59.5.938. [DOI] [PubMed] [Google Scholar]