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. 1990 Aug;53(8):691–694. doi: 10.1136/jnnp.53.8.691

The treatment of Gilles de la Tourette syndrome by limbic leucotomy.

M Robertson 1, M Doran 1, M Trimble 1, A J Lees 1
PMCID: PMC488174  PMID: 2213047

Abstract

A patient with Gilles de la Tourette syndrome and severe self-injurious compulsions who had failed to respond to drug treatment and behavioural therapy obtained a complete and sustained resolution of his destructive behaviour and improvement in his tics following bilateral limbic leucotomy.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baker E. F. Gilles de la Tourette Syndrome Treated by Bimedial Frontal Leucotomy. Can Med Assoc J. 1962 Apr 21;86(16):746–747. [PMC free article] [PubMed] [Google Scholar]
  2. Chase T. N., Geoffrey V., Gillespie M., Burrows G. H. Structural and functional studies of Gilles de la Tourette syndrome. Rev Neurol (Paris) 1986;142(11):851–855. [PubMed] [Google Scholar]
  3. Gadoth N., Gordon C. R., Streifler J. Naloxone in Gilles de la Tourette's syndrome. Ann Neurol. 1987 Apr;21(4):415–415. doi: 10.1002/ana.410210421. [DOI] [PubMed] [Google Scholar]
  4. Guttman N., Baltimore D. Morphogenesis of poliovirus. IV. existence of particles sedimenting at 150S and having the properties of provirion. J Virol. 1977 Aug;23(2):363–367. doi: 10.1128/jvi.23.2.363-367.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Haber S. N., Kowall N. W., Vonsattel J. P., Bird E. D., Richardson E. P., Jr Gilles de la Tourette's syndrome. A postmortem neuropathological and immunohistochemical study. J Neurol Sci. 1986 Sep;75(2):225–241. doi: 10.1016/0022-510x(86)90097-3. [DOI] [PubMed] [Google Scholar]
  6. Hassler R., Dieckmann G. Traitement stéréotaxique des tics et cris inarticulés ou coprolaliques considérés comme phénomène d'obsession motrice au cours de la maladie de Gilles de la Tourette. Rev Neurol (Paris) 1970 Aug;123(2):89–100. [PubMed] [Google Scholar]
  7. Mitchell-Heggs N., Kelly D., Richardson A. Stereotactic limbic leucotomy--a follow-up at 16 months. Br J Psychiatry. 1976 Mar;128:226–240. doi: 10.1192/bjp.128.3.226. [DOI] [PubMed] [Google Scholar]
  8. Nádvorník P., Sramka M., Lisý L., Svicka I. Experiences with dentatotomy. Confin Neurol. 1972;34(5):320–324. doi: 10.1159/000103076. [DOI] [PubMed] [Google Scholar]
  9. Pauls D. L., Leckman J. F. The inheritance of Gilles de la Tourette's syndrome and associated behaviors. Evidence for autosomal dominant transmission. N Engl J Med. 1986 Oct 16;315(16):993–997. doi: 10.1056/NEJM198610163151604. [DOI] [PubMed] [Google Scholar]
  10. Richardson A. Stereotactic limbic leucotomy: surgical technique. Postgrad Med J. 1973 Dec;49(578):860–864. doi: 10.1136/pgmj.49.578.860. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. STEVENS H. THE SYNDROME OF GILLES DE LA TOURETTE AND ITS TREATMENT: REPORT OF A CASE. Med Ann Dist Columbia. 1964 Jun;33:277–279. [PubMed] [Google Scholar]
  12. Talairach J., Bancaud J., Geier S., Bordas-Ferrer M., Bonis A., Szikla G., Rusu M. The cingulate gyrus and human behaviour. Electroencephalogr Clin Neurophysiol. 1973 Jan;34(1):45–52. doi: 10.1016/0013-4694(73)90149-1. [DOI] [PubMed] [Google Scholar]
  13. WHITTY C. W. M., DUFFIELD J. E., TOV' P. M., CAIRNS H. Anterior cingulectomy in the treatment of mental disease. Lancet. 1952 Mar 8;1(6706):475–481. doi: 10.1016/s0140-6736(52)90051-2. [DOI] [PubMed] [Google Scholar]

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