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. 1991 Jun;54(6):516–519. doi: 10.1136/jnnp.54.6.516

Diurnal variation of essential and physiological tremor.

J J van Hilten 1, J G van Dijk 1, R J Dunnewold 1, E A van der Velde 1, B Kemp 1, P van Brummelen 1, J A van der Krogt 1, R A Roos 1, O J Buruma 1
PMCID: PMC488590  PMID: 1880513

Abstract

Evaluations were made of the diurnal variations of tremor power at rest, after fatigue and after mass loading, and plasma norepinephrine in patients with familial essential tremor and normal subjects. Diurnal tremor power rhythms for both essential and physiological tremor pursued identical temporal profiles. Plasma norepinephrine levels followed a congruent diurnal pattern with later peak values than the peak values of tremor power. Sympathetic nervous system activity is unlikely to be the cause of diurnal tremor power variation. The consistent diurnal rhythm of tremor power may affect dosage schemes of tremorolytic drugs.

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Selected References

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  1. Chang P. C., van der Krogt J. A., van Brummelen P. Demonstration of neuronal and extraneuronal uptake of circulating norepinephrine in the forearm. Hypertension. 1987 Jun;9(6):647–653. doi: 10.1161/01.hyp.9.6.647. [DOI] [PubMed] [Google Scholar]
  2. Cleeves L., Findley L. J. Variability in amplitude of untreated essential tremor. J Neurol Neurosurg Psychiatry. 1987 Jun;50(6):704–708. doi: 10.1136/jnnp.50.6.704. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Elble R. J. Physiologic and essential tremor. Neurology. 1986 Feb;36(2):225–231. doi: 10.1212/wnl.36.2.225. [DOI] [PubMed] [Google Scholar]
  4. Esler M., Willett I., Leonard P., Hasking G., Johns J., Little P., Jennings G. Plasma noradrenaline kinetics in humans. J Auton Nerv Syst. 1984 Sep;11(2):125–144. doi: 10.1016/0165-1838(84)90071-7. [DOI] [PubMed] [Google Scholar]
  5. Fellows I. W., Macdonald I. A., Wharrad H. J., Birmingham A. T. Low plasma concentrations of adrenaline and physiological tremor in man. J Neurol Neurosurg Psychiatry. 1986 Apr;49(4):396–399. doi: 10.1136/jnnp.49.4.396. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Gerstenbrand F., Klingler D., Pfeiffer B. Der essentielle Tremor, Phänomenologie und Epidemiologie. Nervenarzt. 1982 Jan;53(1):46–53. [PubMed] [Google Scholar]
  7. Koller W. C., Royse V. L. Time course of a single oral dose of propranolol in essential tremor. Neurology. 1985 Oct;35(10):1494–1498. doi: 10.1212/wnl.35.10.1494. [DOI] [PubMed] [Google Scholar]
  8. Larsen T. A., Calne D. B. Essential tremor. Clin Neuropharmacol. 1983;6(3):185–206. doi: 10.1097/00002826-198309000-00002. [DOI] [PubMed] [Google Scholar]
  9. MARSHALL J. Observations on essential tremor. J Neurol Neurosurg Psychiatry. 1962 May;25:122–125. doi: 10.1136/jnnp.25.2.122. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. MARSHALL J. The effect of ageing upon physiological tremor. J Neurol Neurosurg Psychiatry. 1961 Feb;24:14–17. doi: 10.1136/jnnp.24.1.14. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Marsden C. D., Foley T. H., Owen D. A., McAllister R. G. Peripheral beta-adrenergic receptors concerned with tremor. Clin Sci. 1967 Aug;33(1):53–65. [PubMed] [Google Scholar]
  12. Marsden C. D., Meadows J. C., Lange G. W., Watson R. S. Variations in human physiological finger tremor, with particular reference to changes with age. Electroencephalogr Clin Neurophysiol. 1969 Aug;27(2):169–178. doi: 10.1016/0013-4694(69)90170-9. [DOI] [PubMed] [Google Scholar]
  13. Millar-Craig M. W., Bishop C. N., Raftery E. B. Circadian variation of blood-pressure. Lancet. 1978 Apr 15;1(8068):795–797. doi: 10.1016/s0140-6736(78)92998-7. [DOI] [PubMed] [Google Scholar]
  14. Moore-Ede M. C., Czeisler C. A., Richardson G. S. Circadian timekeeping in health and disease. Part 1. Basic properties of circadian pacemakers. N Engl J Med. 1983 Aug 25;309(8):469–476. doi: 10.1056/NEJM198308253090806. [DOI] [PubMed] [Google Scholar]
  15. Shahani B. T., Young R. R. Physiological and pharmacological aids in the differential diagnosis of tremor. J Neurol Neurosurg Psychiatry. 1976 Aug;39(8):772–783. doi: 10.1136/jnnp.39.8.772. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Sirgo M. A., Mills R. J., DeQuattro V. Effects of antihypertensive agents on circadian blood pressure and heart rate patterns. Review. Arch Intern Med. 1988 Dec;148(12):2547–2552. [PubMed] [Google Scholar]
  17. Stiles R. N. Mechanical and neural feedback factors in postural hand tremor of normal subjects. J Neurophysiol. 1980 Jul;44(1):40–59. doi: 10.1152/jn.1980.44.1.40. [DOI] [PubMed] [Google Scholar]
  18. Turton M. B., Deegan T. Circadian variations of plasma catecholamine, cortisol and immunoreactive insulin concentrations in supine subjects. Clin Chim Acta. 1974 Sep 30;55(3):389–397. doi: 10.1016/0009-8981(74)90014-x. [DOI] [PubMed] [Google Scholar]
  19. Tyrer P. J., Bond A. J. Diurnal variation in physiological tremor. Electroencephalogr Clin Neurophysiol. 1974 Jul;37(1):35–40. doi: 10.1016/0013-4694(74)90243-0. [DOI] [PubMed] [Google Scholar]

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