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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1982 Nov;45(11):962–968. doi: 10.1136/jnnp.45.11.962

Mild senile dementia of Alzheimer type: research diagnostic criteria, recruitment, and description of a study population.

L Berg, C P Hughes, L A Coben, W L Danziger, R L Martin, J Knesevich
PMCID: PMC491630  PMID: 7175540

Abstract

Clinical investigations of senile dementia of the Alzheimer type require establishment of explicit clinical diagnostic criteria before histological confirmation is possible. Criteria for selection of mildly impaired subjects with senile dementia of Alzheimer type, free of other major disease, are proposed. Problems of recruitment of this select population for a longitudinal study are discussed. A study population with matched healthy control subjects has been enrolled and described. Short term follow-up has provided preliminary support for the diagnostic criteria.

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Selected References

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