Skip to main content
PMC home page
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1977 Apr;40(4):331–335. doi: 10.1136/jnnp.40.4.331

Diabetes mellitus in normal pressure hydrocephalus.

L Jacobs
PMCID: PMC492699  PMID: 874510

Abstract

Seventeen of 33 patients (51.5%) with normal pressure hydrocephalus were discovered to have diabetes mellitus. This was significantly greater than the 12.1% incidence found in age-matched control subjects. The diabetes was not accounted for either by the patients' ages nor by their physical inactivity due to hospitalisation. Diabetes mellitus concurrent with normal pressure hydrocephalus may result from involvement of hypothalamic and brainstem autonomic structures by the expanding ventricles during the evolution of hydrocephalus.

Full text

PDF
335

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ADAMS R. D., FISHER C. M., HAKIM S., OJEMANN R. G., SWEET W. H. SYMPTOMATIC OCCULT HYDROCEPHALUS WITH "NORMAL" CEREBROSPINAL-FLUID PRESSURE.A TREATABLE SYNDROME. N Engl J Med. 1965 Jul 15;273:117–126. doi: 10.1056/NEJM196507152730301. [DOI] [PubMed] [Google Scholar]
  2. ANAND B. K., DUA S. Blood sugar changes induced by electrical stimulation of the hypothalamus in cat. Indian J Med Res. 1955 Jan;43(1):123–127. [PubMed] [Google Scholar]
  3. ANDERSON E., RIOCH D. M., HAYMAKER W. Disturbances in blood sugar regulation in animals subjected to transection of the brain stem. Acta Neuroveg (Wien) 1952;5(1-2):132–164. doi: 10.1007/BF01232007. [DOI] [PubMed] [Google Scholar]
  4. Andres R. Aging and diabetes. Med Clin North Am. 1971 Jul;55(4):835–846. doi: 10.1016/s0025-7125(16)32479-8. [DOI] [PubMed] [Google Scholar]
  5. Beck P., Parker M. L., Daughaday W. H. Paradoxical hypersecretion of growth hormone in response to glucose. J Clin Endocrinol Metab. 1966 Apr;26(4):463–469. doi: 10.1210/jcem-26-4-463. [DOI] [PubMed] [Google Scholar]
  6. Hakim S., Adams R. D. The special clinical problem of symptomatic hydrocephalus with normal cerebrospinal fluid pressure. Observations on cerebrospinal fluid hydrodynamics. J Neurol Sci. 1965 Jul-Aug;2(4):307–327. doi: 10.1016/0022-510x(65)90016-x. [DOI] [PubMed] [Google Scholar]
  7. Jacobs L., Conti D., Kinkel W. R., Manning E. J. "Normal-pressure" hydrocephalus. Relationship of clinical and radiographic findings to improvement following shunt surgery. JAMA. 1976 Feb 2;235(5):510–512. doi: 10.1001/jama.235.5.510. [DOI] [PubMed] [Google Scholar]
  8. Jacobs L., Kinkel W. Computerized axial transverse tomography in normal pressure hydrocephalus. Neurology. 1976 Jun;26(6 Pt 1):501–507. doi: 10.1212/wnl.26.6.501. [DOI] [PubMed] [Google Scholar]
  9. James A. E., Jr, Strecker E. P., Novak G., Burns B. Correlation of serial cisternograms and cerebrospinal fluid pressure measurements in experimental communicating hydrocephalus. Neurology. 1973 Nov;23(11):1226–1233. doi: 10.1212/wnl.23.11.1226. [DOI] [PubMed] [Google Scholar]
  10. MATTHEWS W. B. Discussion on some clinical, genetic and biochemical aspects of metabolic disorders of the nervous system: metabolic disease of the nervous system: clinical aspects. Proc R Soc Med. 1958 Oct;51(10):859–863. [PMC free article] [PubMed] [Google Scholar]
  11. PIERCE N. H. GLUCOSE TOLERANCE AND GLYCOSURIA IN THE GENERAL POPULATION: REPORT OF A WORKING PARTY APPOINTED BY THE COLLEGE OF GENERAL PRACTITIONERS. Br Med J. 1963 Sep 14;2(5358):655–659. doi: 10.1136/bmj.2.5358.655. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. STEINKE J., TYLER H. R. THE ASSOCIATION OF AMYOTROPHIC LATERAL SCLEROSIS (MOTOR NEURON DISEASE) AND CARBOHYDRATE INTOLERANCE, A CLINICAL STUDY. Metabolism. 1964 Nov;13:1376–1381. doi: 10.1016/0026-0495(64)90158-1. [DOI] [PubMed] [Google Scholar]
  13. Schalch D. S., McFarlin D. E., Barlow M. H. An unusual form of diabetes mellitus in ataxia telangiectasia. N Engl J Med. 1970 Jun 18;282(25):1396–1402. doi: 10.1056/NEJM197006182822503. [DOI] [PubMed] [Google Scholar]
  14. Standardization of the oral glucose tolerance test. Report of the Committee on Statistics of the American Diabetes Association June 14, 1968. Diabetes. 1969 May;18(5):299–307. doi: 10.2337/diab.18.5.299. [DOI] [PubMed] [Google Scholar]
  15. UNGER R. H. The standard two-hour oral glucose tolerance test in the diagnosis of diabetes mellitus in subjects without fasting hyperglycemia. Ann Intern Med. 1957 Dec;47(6):1138–1153. doi: 10.7326/0003-4819-47-6-1138. [DOI] [PubMed] [Google Scholar]
  16. ZALME E., KNOWLES H. C., Jr A PLEA FOR PLASMA SUGAR. Diabetes. 1965 Mar;14:165–166. doi: 10.2337/diab.14.3.165. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES