Abstract
A review of histopathology reports on 2046 patients in the large bowel cancer project showed considerable observer variation in histological grading. Dukes staging, and lymph node harvest. These parameters have a well-established relationship to prognosis, but, if they are to be applied for both clinical and research purposes, they must be assessed consistently. A minimal level of information which should be recorded from a resection specimen is suggested, with a description of the methods by which this information can be obtained.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Buckwalter J. A., Jr, Kent T. H. Prognosis and surgical pathology of carcinoma of the colon. Surg Gynecol Obstet. 1973 Mar;136(3):465–472. [PubMed] [Google Scholar]
- DUKES C. E., BUSSEY H. J. The spread of rectal cancer and its effect on prognosis. Br J Cancer. 1958 Sep;12(3):309–320. doi: 10.1038/bjc.1958.37. [DOI] [PMC free article] [PubMed] [Google Scholar]
- GRINNELL R. S., LANE N. Benign and malignant adenomatous polyps and papillary adenomas of the colon and rectum; an analysis of 1,856 tumors in 1,335 patients. Int Abstr Surg. 1958 Jun;106(6):519–538. [PubMed] [Google Scholar]
- Shepherd J. M., Jones J. S. Adenocarcinoma of the large bowel. Br J Cancer. 1971 Dec;25(4):680–690. doi: 10.1038/bjc.1971.83. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Talbot I. C., Ritchie S., Leighton M. H., Hughes A. O., Bussey H. J., Morson B. C. The clinical significance of invasion of veins by rectal cancer. Br J Surg. 1980 Jun;67(6):439–442. doi: 10.1002/bjs.1800670619. [DOI] [PubMed] [Google Scholar]