Abstract
In an extensive study of Huntington's chorea in Queensland evidence was found to support an old observation that the magnitude of the variation in the symptom complex of the disease between different families is sufficient to suggest that there may be more than one form of Huntington's chorea allele present in the community. Analysis of data concerning age at onset indicates that at least two separate forms of the disorder may exist.
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- BITTENBENDER J. B., QUADFASEL F. A. Rigid and akinetic forms of Huntington's chorea. Arch Neurol. 1962 Oct;7:275–288. doi: 10.1001/archneur.1962.04210040027003. [DOI] [PubMed] [Google Scholar]
- CHANDLER J. H., REED T. E., DEJONG R. N. Huntington's chorea in Michigan. III. Clinical observations. Neurology. 1960 Feb;10:148–153. doi: 10.1212/wnl.10.2.148. [DOI] [PubMed] [Google Scholar]
- MORTON N. E. The detection and estimation of linkage between the genes for elliptocytosis and the Rh blood type. Am J Hum Genet. 1956 Jun;8(2):80–96. [PMC free article] [PubMed] [Google Scholar]
- MUELLER-KUEPPERS M., STENZEL K. ZUM PROBLEM DER FRUEHMANIFESTATION DER ERBCHOREA. Acta Paedopsychiatr. 1963 Sep-Oct;30:348–355. [PubMed] [Google Scholar]
- Myrianthopoulos N. C. Huntington's chorea. J Med Genet. 1966 Dec;3(4):298–314. doi: 10.1136/jmg.3.4.298. [DOI] [PMC free article] [PubMed] [Google Scholar]
- PARKER N. Observations on Huntington's chorea based on a Queensland survey. Med J Aust. 1958 Mar 15;45(11):351–359. doi: 10.5694/j.1326-5377.1958.tb86365.x. [DOI] [PubMed] [Google Scholar]
- REED T. E., CHANDLER J. H. Huntington's chorea in Michigan. I. Demography and genetics. Am J Hum Genet. 1958 Jun;10(2):201–225. [PMC free article] [PubMed] [Google Scholar]
- TYRER J. H. The differentiation of hysteria from organic neurological disease. Med J Aust. 1957 Apr 27;44(17):566–571. doi: 10.5694/j.1326-5377.1957.tb57472.x. [DOI] [PubMed] [Google Scholar]