Abstract
The concentrations of plasminogen and fast-acting antiplasmin were measured in 65 normal plasmas and matched sera. Concentrations were decreased in serum by 38% for plasminogen and 32% for fast-acting antiplasmin. The decrease in plasminogen level was due to both adsorption of plasminogen to fibrin and reaction with antiplasmin.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- ALKJAERSIG N., FLETCHER A. P., SHERRY S. The mechanism of clot dissolution by plasmin. J Clin Invest. 1959 Jul;38(7):1086–1095. doi: 10.1172/JCI103885. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Cederholm-Williams S. A., Swain A. The effect of fibrinogen degradation products and some lysine analogues on the dissociation of plasmin(ogen)-fibrin complexes. Thromb Res. 1979;16(5-6):705–713. doi: 10.1016/0049-3848(79)90214-7. [DOI] [PubMed] [Google Scholar]
- Collen D., Wiman B. Fast-acting plasmin inhibitor in human plasma. Blood. 1978 Apr;51(4):563–569. [PubMed] [Google Scholar]
- Hender U., Nilsson I. M., Robertson B. Determination of plasminogen in clots and thrombi. Thromb Diath Haemorrh. 1966 Jul 31;16(1):38–50. [PubMed] [Google Scholar]
- Ogston D., Ogston C. M., Fullerton H. W. The plasminogen content of thrombi. Thromb Diath Haemorrh. 1966 Jan 31;15(1):220–230. [PubMed] [Google Scholar]
- Teger-Nilsson A. C., Friberger P., Gyzander E. Determination of a new rapid plasmin inhibitor in human blood by means of a plasmin specific tripeptide substrate. Scand J Clin Lab Invest. 1977 Sep;37(5):403–409. [PubMed] [Google Scholar]
- VERMYLEN C., DE VREKER R. A., VERSTRAETE M. A rapid enzymatic method for assay of fibrinogen fibrin polymerization time (FPT test). Clin Chim Acta. 1963 May;8:418–424. doi: 10.1016/0009-8981(63)90080-9. [DOI] [PubMed] [Google Scholar]
- Wiman B., Collen D. Molecular mechanism of physiological fibrinolysis. Nature. 1978 Apr 6;272(5653):549–550. doi: 10.1038/272549a0. [DOI] [PubMed] [Google Scholar]
- Wiman B., Collen D. On the kinetics of the reaction between human antiplasmin and plasmin. Eur J Biochem. 1978 Mar 15;84(2):573–578. doi: 10.1111/j.1432-1033.1978.tb12200.x. [DOI] [PubMed] [Google Scholar]
- Wiman B., Lijnen H. R., Collen D. On the specific interaction between the lysine-binding sites in plasmin and complementary sites in alpha2-antiplasmin and in fibrinogen. Biochim Biophys Acta. 1979 Jul 25;579(1):142–154. doi: 10.1016/0005-2795(79)90094-1. [DOI] [PubMed] [Google Scholar]
- Wiman B., Wallén P. The specific interaction between plasminogen and fibrin. A physiological role of the lysine binding site in plasminogen. Thromb Res. 1977 Feb;10(2):213–222. doi: 10.1016/0049-3848(77)90003-2. [DOI] [PubMed] [Google Scholar]