Abstract
Abnormalities of the innervation of the oesophagus have been shown in 18 out of 20 unselected diabetics without clinical dysphagia or neuropathy. The changes appear to be in the axons of the extrinsic and intrinsic parasympathetic fibres. It is probable that, as in the peripheral nerves, the major changes are in the Schwann cells, although here the affected fibres are unmyelinated.
Full text
PDF



Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- AGOSTONI E., CHINNOCK J. E., DE DALY M. B., MURRAY J. G. Functional and histological studies of the vagus nerve and its branches to the heart, lungs and abdominal viscera in the cat. J Physiol. 1957 Jan 23;135(1):182–205. doi: 10.1113/jphysiol.1957.sp005703. [DOI] [PMC free article] [PubMed] [Google Scholar]
- COUERS C., HILDEBRAND J. LATENT NEUROPATHY IN DIABETES AND ALCOHOLISM: ELECTROMYOGRAPHIC AND HISTOLOGICAL STUDY. Neurology. 1965 Jan;15:19–38. doi: 10.1212/wnl.15.1.19. [DOI] [PubMed] [Google Scholar]
- EVANS D. H., MURRAY J. G. Histological and functional studies on the fibre composition of the vagus nerve of the rabbit. J Anat. 1954 Jul;88(3):320–337. [PMC free article] [PubMed] [Google Scholar]
- Gabella G. Fine structure of the myenteric plexus in the guinea-pig ileum. J Anat. 1972 Jan;111(Pt 1):69–97. [PMC free article] [PubMed] [Google Scholar]
- Keen J. A. A note of the fibre composition of the vagus nerve in man. S Afr Med J. 1966 Nov 5;40(40):981–984. [PubMed] [Google Scholar]
- MALINS J. M., FRENCH J. M. Diabetic diarrhoea. Q J Med. 1957 Oct;26(104):467–480. [PubMed] [Google Scholar]
- Mandelstam P., Lieber A. Esophageal dysfunction in diabetic neuropathy-gastroenteropathy. Clinical and roentgenological manifestations. JAMA. 1967 Aug 21;201(8):582–586. doi: 10.1001/jama.201.8.582. [DOI] [PubMed] [Google Scholar]
- Misiewicz J. J., Waller S. L., Anthony P. P., Gummer J. W. Achalasia of the cardia: pharmacology and histopathology of isolated cardiac sphincteric muscle from patients with and without achalasia. Q J Med. 1969 Jan;38(149):17–30. [PubMed] [Google Scholar]
- Smith B. Myenteric plexus in Hirschsprung's disease. Gut. 1967 Jun;8(3):308–312. doi: 10.1136/gut.8.3.308. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Thomas P. K. Diabetic neuropathy: morphological aspects. Proc R Soc Med. 1967 Feb;60(2):145–145. [PMC free article] [PubMed] [Google Scholar]
- Vela A. R., Balart L. Esophageal motor manifestations in diabetes mellitus. Am J Surg. 1970 Jan;119(1):21–26. doi: 10.1016/0002-9610(70)90005-x. [DOI] [PubMed] [Google Scholar]
- Zitomer B. R., Gramm H. F., Kozak G. P. Gastric neuropathy in diabetes mellitus: clinical and radiologic observations. Metabolism. 1968 Mar;17(3):199–211. doi: 10.1016/0026-0495(68)90123-6. [DOI] [PubMed] [Google Scholar]