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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1982 Feb;35(2):215–218. doi: 10.1136/jcp.35.2.215

Failure of the fluorescent antibody reaction to identify penicillinase-producing gonococci.

S A Waitkins, R D Anderson
PMCID: PMC497501  PMID: 6802878

Abstract

The fluorescent antibody test is now widely used to confirm the identity of Neisseria gonorrhoeae but may fail to identify penicillinase-producing strains (PPNG). This problem arises when conjugates are used that incorporate only gonococci that are not penicillinase-producers. We have shown that conjugates prepared from mixtures of PPNG and non-penicillinase producing gonococci give good fluorescent reactions. This difference in the reactions of PPNG strains is clearly related to their penicillinase-producing abilities, further study of the antigenic relation between penicillinase production and the antigenic structure of N gonorrhoeae is evidently required.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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