Abstract
Thirteen patients are described who, on routine endoscopy of the upper gastrointestinal (GI) tract, were found to show a characteristic appearance in the proximal duodenum. This consisted of multiple small mucosal nodules, predominantly in the anterior wall. All cases were biopsied, and showed identical histological appearances of heterotopic gastric mucosa of body type. The incidence of this condition is probably much higher than reported previously, and may be present in up to 2% of the population. In all our patients a diagnosis was reached, other than heterotopic gastric mucosa, to explain the GI tract symptoms. In none was a healed or active duodenal ulcer evident and in none was there a history of a pre-existing ulcer. In our opinion these nodules are probably of little or no clinical significance.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- JAMES A. H. GASTRIC EPITHELIUM IN THE DUODENUM. Gut. 1964 Aug;5:285–294. doi: 10.1136/gut.5.4.285. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Johansen A., Hansen O. H. Heterotopic gastric epithelium in the duodenum and its correlation to gastric disease and acid level. Acta Pathol Microbiol Scand A. 1973 Sep;81(5):676–680. doi: 10.1111/j.1699-0463.1973.tb03560.x. [DOI] [PubMed] [Google Scholar]
- Johansen A., Hansen O. H. Macroscopically demonstrable heterotopic gastric mucosa in the duodenum. Scand J Gastroenterol. 1973;8(1):59–63. [PubMed] [Google Scholar]
- Kreuning J., Bosman F. T., Kuiper G., Wal A. M., Lindeman J. Gastric and duodenal mucosa in 'healthy' individuals. An endoscopic and histopathological study of 50 volunteers. J Clin Pathol. 1978 Jan;31(1):69–77. doi: 10.1136/jcp.31.1.69. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Langkemper R., Hoek A. C., Dekker W., Op den Orth J. O. Elevated lesions in the duodenal bulb caused by heterotopic gastric mucosa. Radiology. 1980 Dec;137(3):621–624. doi: 10.1148/radiology.137.3.7444047. [DOI] [PubMed] [Google Scholar]
- Lee S. M., Mosenthal W. T., Weismann R. E. Tumorous heterotopic gastric mucosa in the small intestine. Arch Surg. 1970 May;100(5):619–622. doi: 10.1001/archsurg.1970.01340230085022. [DOI] [PubMed] [Google Scholar]
- Wolff M. Heterotopic gastric epithelium in the rectum: a report of three new cases with a review of 87 cases of gastric heterotopia in the alimentary canal. Am J Clin Pathol. 1971 May;55(5):604–616. doi: 10.1093/ajcp/55.5.604. [DOI] [PubMed] [Google Scholar]