Abstract
The action of ozone generated from a small domestic device was examined with a view to using it in clinical isolation units accommodating immunosuppressed patients. Over a six-hour period in an average size room the device did not generate sufficient ozone to suppress bacterial and fungal growth. A useful bactericidal action, against a variety of human pathogens was achieved with ozone concentrations between 0.3 to 0.9 ppm. Bactericidal ozone concentrations are close to the limit permitted for human exposure however and further experiments are indicated.
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- Broadwater W. T., Hoehn R. C., King P. H. Sensitivity of three selected bacterial species to ozone. Appl Microbiol. 1973 Sep;26(3):391–393. doi: 10.1128/am.26.3.391-393.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Goldstein E., Bartlema H. C., van der Ploeg M., van Duijn P., van der Stap J. G., Lippert W. Effect of ozone on lysosomal enzymes of alveolar macrophages engaged in phagocytosis and killing of inhaled Staphylococcus aureus. J Infect Dis. 1978 Sep;138(3):299–311. doi: 10.1093/infdis/138.3.299. [DOI] [PubMed] [Google Scholar]
- Hamelin C., Chung Y. S. Optimal conditions for mutagenesis by ozone in Escherichia coli K12. Mutat Res. 1974 Sep;24(3):271–279. doi: 10.1016/0027-5107(74)90175-4. [DOI] [PubMed] [Google Scholar]
- Hibben C. R., Stotzky G. Effects of ozone on the germination of fungus spores. Can J Microbiol. 1969 Oct;15(10):1187–1196. doi: 10.1139/m69-215. [DOI] [PubMed] [Google Scholar]
- Illing J. W., Miller F. J., Gardner D. E. Decreased resistance to infection in exercised mice exposed to NO2 and O3. J Toxicol Environ Health. 1980 Jul;6(4):843–851. doi: 10.1080/15287398009529902. [DOI] [PubMed] [Google Scholar]
- Masaoka T., Kubota Y., Namiuchi S., Takubo T., Ueda T., Shibata H., Nakamura H., Yoshitake J., Yamayoshi T., Doi H. Ozone decontamination of bioclean rooms. Appl Environ Microbiol. 1982 Mar;43(3):509–513. doi: 10.1128/aem.43.3.509-513.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Peterson M. L., Harder S., Rummo N., House D. Effect of ozone on leukocyte function in exposed human subjects. Environ Res. 1978 Jun;15(3):485–493. doi: 10.1016/0013-9351(78)90127-5. [DOI] [PubMed] [Google Scholar]