Abstract
Over the past 25 years, 2921 appendicectomies were performed at this hospital. All were subjected to routine histopathological examination. In 95% of cases, histopathological examination did not add any further information but in 153 (5%) cases, clinically important pathological findings were detected for the first time. Seventy (2.3%) specimens showed typical evidence of tuberculosis. Parasitic infestation was detected in 75 (2.5%), including enterobiasis (1.4%), amoebiasis (0.5%), ascariasis (0.5%), ascariasis with trichuriasis (0.05%), and taeniasis (0.05%). Other lesions found were mucocele (0.1%) and carcinoid tumour (0.1%). It is concluded that routine histopathological examination of all appendicectomy specimens should be performed to avoid missing any clinically important and treatable condition.
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- BEFELER D. RECURRENT APPENDICITIS. INCIDENCE AND PROPHYLAXIS. Arch Surg. 1964 Oct;89:666–668. doi: 10.1001/archsurg.1964.01320040082013. [DOI] [PubMed] [Google Scholar]
- BOBROW M. L., FRIEDMAN S. Tuberculous appendicitis. Am J Surg. 1956 Mar;91(3):389–393. doi: 10.1016/0002-9610(56)90177-5. [DOI] [PubMed] [Google Scholar]
- Bhasin V., Chopra P., Kapur B. M. Acute tubercular appendicitis. Int Surg. 1977 Oct;62(10):563–564. [PubMed] [Google Scholar]
- Brooks S. G., Hughes R. G. Selective histopathology for appendix specimens. Lancet. 1987 Dec 19;2(8573):1456–1456. doi: 10.1016/s0140-6736(87)91146-9. [DOI] [PubMed] [Google Scholar]
- Chan W., Fu K. H. Value of routine histopathological examination of appendices in Hong Kong. J Clin Pathol. 1987 Apr;40(4):429–433. doi: 10.1136/jcp.40.4.429. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Coghill S. B. Routine examination of appendices in Hong Kong. J Clin Pathol. 1987 Nov;40(11):1388–1388. doi: 10.1136/jcp.40.11.1388-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Corey L., Whitley R. J., Stone E. F., Mohan K. Difference between herpes simplex virus type 1 and type 2 neonatal encephalitis in neurological outcome. Lancet. 1988 Jan 2;1(8575-6):1–4. doi: 10.1016/s0140-6736(88)90997-x. [DOI] [PubMed] [Google Scholar]
- Corey L., Whitley R. J., Stone E. F., Mohan K. Difference between herpes simplex virus type 1 and type 2 neonatal encephalitis in neurological outcome. Lancet. 1988 Jan 2;1(8575-6):1–4. doi: 10.1016/s0140-6736(88)90997-x. [DOI] [PubMed] [Google Scholar]
- Cromartie A. D., Jr, Kovalcik P. J. Incidental appendectomy at the time of surgery for ectopic pregnancy. Am J Surg. 1980 Feb;139(2):244–246. doi: 10.1016/0002-9610(80)90264-0. [DOI] [PubMed] [Google Scholar]
- Fichtelius K. E. The mammalian equivalent to bursa Fabricii of birds. Exp Cell Res. 1967 Apr;46(1):231–234. doi: 10.1016/0014-4827(67)90427-2. [DOI] [PubMed] [Google Scholar]
- Higa E., Rosai J., Pizzimbono C. A., Wise L. Mucosal hyperplasia, mucinous cystadenoma, and mucinous cystadenocarcinoma of the appendix. A re-evaluation of appendiceal "mucocele". Cancer. 1973 Dec;32(6):1525–1541. doi: 10.1002/1097-0142(197312)32:6<1525::aid-cncr2820320632>3.0.co;2-c. [DOI] [PubMed] [Google Scholar]
- Jones R. A., MacFarlane A. Carcinomas and carcinoid tumours of the appendix in a district general hospital. J Clin Pathol. 1976 Aug;29(8):687–692. doi: 10.1136/jcp.29.8.687. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Konda S., Harris T. N. Effect of appendectomy and of the thymectomy, with x-irradiation, on the production of antibodies to two protein antigens in young rabbits. J Immunol. 1966 Dec;97(6):805–814. [PubMed] [Google Scholar]
- Lau W. Y., Fan S. T., Yiu T. F., Chu K. W., Suen H. C., Wong K. K. The clinical significance of routine histopathologic study of the resected appendix and safety of appendiceal inversion. Surg Gynecol Obstet. 1986 Mar;162(3):256–258. [PubMed] [Google Scholar]
- MORRISON H., MIXTER C. G., SCHELESINGER M. J., OBER W. B. Tuberculosis localized in the vermiform appendix. N Engl J Med. 1952 Feb 28;246(9):329–331. doi: 10.1056/NEJM195202282460903. [DOI] [PubMed] [Google Scholar]
- Miranda R., Johnston A. D., O'Leary J. P. Incidental appendectomy: frequency of pathologic abnormalities. Am Surg. 1980 Jun;46(6):355–357. [PubMed] [Google Scholar]
- Mittal V. K., Khanna S. K., Gupta N. M., Aikat M. Isolated tuberculosis of appendix. Am Surg. 1975 Mar;41(3):172–174. [PubMed] [Google Scholar]
- Moertel C. G., Dockerty M. B., Judd E. S. Carcinoid tumors of the vermiform appendix. Cancer. 1968 Feb;21(2):270–278. doi: 10.1002/1097-0142(196802)21:2<270::aid-cncr2820210217>3.0.co;2-9. [DOI] [PubMed] [Google Scholar]
- Savrin R. A., Clausen K., Martin E. W., Jr, Cooperman M. Chronic and recurrent appendicitis. Am J Surg. 1979 Mar;137(3):355–357. doi: 10.1016/0002-9610(79)90066-7. [DOI] [PubMed] [Google Scholar]
- Selective histopathology of appendicectomy specimens. Lancet. 1988 Jan 16;1(8577):110–111. [PubMed] [Google Scholar]
- Toma V. A., Reteif F. P. Human vermiform appendix. Immunocompetent cell topography and cell-to-cell interactions in situ. J Immunol Methods. 1978;20:333–347. doi: 10.1016/0022-1759(78)90269-7. [DOI] [PubMed] [Google Scholar]
- Viñuela A., Fernandez-Rojo F., Martinez-Merino A. Oxyuris granulomas of pelvic peritoneum and appendicular wall. Histopathology. 1979 Jan;3(1):69–77. doi: 10.1111/j.1365-2559.1979.tb02982.x. [DOI] [PubMed] [Google Scholar]