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. 1992 Sep;76(9):563–566. doi: 10.1136/bjo.76.9.563

Congenital adenoma of the iris and ciliary body: light and electron microscopic observations.

I G Rennie 1, M A Parsons 1, C A Palmer 1
PMCID: PMC504350  PMID: 1420064

Abstract

A 23-year-old man had a lesion in the right inferior iris which appeared to have enlarged since it was first seen when the patient was aged 5 years. The lesion was excised by a partial iridocyclectomy. Histopathologically the neoplasm was composed of both pigmented and non-pigmented cells. Pseudoacini, containing acid mucopolysaccharides, were present throughout the tumour matrix. Electron microscopically the non-pigmented cells were found to possess a convoluted plasmalemma, abundant rough endoplasmic reticulum, and numerous desmosomes and gap junctions. The pigmented cells contained large, round, mature melanosomes, occasional premelanosomes, and desmosomes, which resembled the posterior pigment epithelium of the iris. The intercellular matrix contained fine collagen fibrils resembling vitreous. We believe that this neoplasm represents a congenital adenoma of the ciliary body and iris.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bateman J. B., Foos R. Y. Coronal adenomas. Arch Ophthalmol. 1979 Dec;97(12):2379–2384. doi: 10.1001/archopht.1979.01020020595020. [DOI] [PubMed] [Google Scholar]
  2. Burch P. G., Maumenee A. E. Iridocyclectomy for benign tumors of the ciliary body. Am J Ophthalmol. 1967 Mar;63(3):447–452. doi: 10.1016/0002-9394(67)90242-5. [DOI] [PubMed] [Google Scholar]
  3. Chang M., Shields J. A., Wachtel D. L. Adenoma of the pigment epithelium of the ciliary body simulating a malignant melanoma. Am J Ophthalmol. 1979 Jul;88(1):40–44. doi: 10.1016/0002-9394(79)90750-5. [DOI] [PubMed] [Google Scholar]
  4. Doro S., Werblin T. P., Haas B., Iwamoto T., Jakobiec F. A. Fetal adenoma of the pigmented ciliary epithelium associated with persistent hyperplastic primary vitreous. Ophthalmology. 1986 Oct;93(10):1343–1350. doi: 10.1016/s0161-6420(86)33568-1. [DOI] [PubMed] [Google Scholar]
  5. Dryja T. P., Albert D. M., Horns D. Adenocarcinoma arising from the epithelium of the ciliary body. Ophthalmology. 1981 Dec;88(12):1290–1292. doi: 10.1016/s0161-6420(81)34863-5. [DOI] [PubMed] [Google Scholar]
  6. Fanta H. Epithelial tumour (adenoma) of the ciliary body and iris. Ophthalmologica. 1977;174(1):55–57. doi: 10.1159/000308577. [DOI] [PubMed] [Google Scholar]
  7. Haddad R., Slezak H. Benign adenoma of the ciliary epithelium with tumour seeding. Ophthalmologica. 1979;178(1-2):67–71. doi: 10.1159/000308808. [DOI] [PubMed] [Google Scholar]
  8. Iliff W. J., Green W. R. The incidence and histology of Fuchs's adenoma. Arch Ophthalmol. 1972 Sep;88(3):249–254. doi: 10.1001/archopht.1972.01000030251004. [DOI] [PubMed] [Google Scholar]
  9. Lommatzsch P., Vorpahl K., Bauke G., Klug H. Uber epitheliale Tumoren des Ziliakörpers--klinische, histologische und elektronenmikroskopische Beobachtungen. Klin Monbl Augenheilkd. 1979 Jan;174(1):34–40. [PubMed] [Google Scholar]
  10. Morris D. A., Henkind P. Neoplasms of the iris pigment epithelium. Am J Ophthalmol. 1968 Jul;66(1):31–41. doi: 10.1016/0002-9394(68)91782-0. [DOI] [PubMed] [Google Scholar]
  11. Offret H., Saraux H. Adenoma of the iris pigment epithelium. Arch Ophthalmol. 1980 May;98(5):875–883. doi: 10.1001/archopht.1980.01020030869014. [DOI] [PubMed] [Google Scholar]
  12. Papale J. J., Akiwama K., Hirose T., Tsubota K., Hanaoka K., Albert D. M. Adenocarcinoma of the ciliary body pigment epithelium in a child. Arch Ophthalmol. 1984 Jan;102(1):100–103. doi: 10.1001/archopht.1984.01040030084042. [DOI] [PubMed] [Google Scholar]
  13. Patrinely J. R., Font R. L., Campbell R. J., Robertson D. M. Hamartomatous adenoma of the nonpigmented ciliary epithelium arising in iris-ciliary body coloboma. Light and electron microscopic observations. Ophthalmology. 1983 Dec;90(12):1540–1547. doi: 10.1016/s0161-6420(83)34351-7. [DOI] [PubMed] [Google Scholar]
  14. Shields J. A., Augsburger J. J., Sanborn G. E., Klein R. M. Adenoma of the iris-pigment epithelium. Ophthalmology. 1983 Jun;90(6):735–739. doi: 10.1016/s0161-6420(83)34499-7. [DOI] [PubMed] [Google Scholar]
  15. Shields J. A., Augsburger J. J., Wallar P. H., Shah H. G. Adenoma of the nonpigmented epithelium of the ciliary body. Ophthalmology. 1983 Dec;90(12):1528–1530. doi: 10.1016/s0161-6420(83)34353-0. [DOI] [PubMed] [Google Scholar]
  16. Stefani F. H., Kment H., Kment M. Adenom des Ziliarkörpers. Klin Monbl Augenheilkd. 1982 Feb;180(2):162–163. doi: 10.1055/s-2008-1055040. [DOI] [PubMed] [Google Scholar]
  17. Streeten B. W., McGraw J. L. Tumor of the ciliary pigment epithelium. Am J Ophthalmol. 1972 Sep;74(3):420–429. doi: 10.1016/0002-9394(72)90901-4. [DOI] [PubMed] [Google Scholar]
  18. Takagi T., Tsuda N., Watanabe F., Takaku I. An epithelioma of the ciliary body. Ophthalmologica. 1987;195(1):13–20. doi: 10.1159/000309774. [DOI] [PubMed] [Google Scholar]
  19. WADSWORTH J. A. C. Epithelial tumors of the ciliary body. Am J Ophthalmol. 1949 Nov;32(11):1487-1501, illust. doi: 10.1016/s0002-9394(49)90369-4. [DOI] [PubMed] [Google Scholar]
  20. Wilensky J. T., Holland M. G. A pigmented tumor of the ciliary body. Arch Ophthalmol. 1974 Sep;92(3):219–220. doi: 10.1001/archopht.1974.01010010227009. [DOI] [PubMed] [Google Scholar]
  21. Zimmerman L. E. The remarkable polymorphism of tumours of the ciliary epithelium. Trans Aust Coll Ophthalmol. 1970;2:114–125. [PubMed] [Google Scholar]
  22. Zimmerman L. E. Verhoeff's "terato-neuroma". A critical reappraisal in light of new observations and current concepts of embryonic tumors. The Fourth Frederick H. Verhoeff Lecture. Am J Ophthalmol. 1971 Dec;72(6):1039–1057. [PubMed] [Google Scholar]

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