Abstract
A 76-year-old man with compressive optic neuropathy secondary to a retrobulbar mass was managed by orbitotomy and removal of the mass. The lesion proved histopathologically to be an unusual orbital melanoma with massive central necrosis. There was no histopathological evidence of congenital melanocytosis. Dermatological and systemic evaluation before and after orbital surgery revealed no evidence of primary melanoma elsewhere. The patient developed hepatic metastasis 2 years after excision of the orbital tumour. It appears that the melanoma was a primary orbital tumour and not a metastatic melanoma from an occult primary lesion.
Full text
PDFImages in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Coppeto J. R., Jaffe R., Gillies C. G. Primary orbital melanoma. Arch Ophthalmol. 1978 Dec;96(12):2255–2258. doi: 10.1001/archopht.1978.03910060551018. [DOI] [PubMed] [Google Scholar]
- Drews R. C. Primary malignant melanoma of the orbit in a Negro. Arch Ophthalmol. 1975 May;93(5):335–336. doi: 10.1001/archopht.1975.01010020347004. [DOI] [PubMed] [Google Scholar]
- Dutton J. J., Anderson R. L., Schelper R. L., Purcell J. J., Tse D. T. Orbital malignant melanoma and oculodermal melanocytosis: report of two cases and review of the literature. Ophthalmology. 1984 May;91(5):497–507. doi: 10.1016/s0161-6420(84)34261-0. [DOI] [PubMed] [Google Scholar]
- Ellis D. S., Spencer W. H., Stephenson C. M. Congenital neurocutaneous melanosis with metastatic orbital malignant melanoma. Ophthalmology. 1986 Dec;93(12):1639–1642. doi: 10.1016/s0161-6420(86)33518-8. [DOI] [PubMed] [Google Scholar]
- Foster J. AN ENCAPSULATED ORBITAL MELANOMA. Br J Ophthalmol. 1944 Jun;28(6):293–296. doi: 10.1136/bjo.28.6.293. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hagler W. S., Brown C. C. Malignant melanoma of the orbit arising in a nevus of Ota. Trans Am Acad Ophthalmol Otolaryngol. 1966 Sep-Oct;70(5):817–822. [PubMed] [Google Scholar]
- Haim T., Meyer E., Kerner H., Zonis S. Oculodermal melanocytosis (nevus of Ota) and orbital malignant melanoma. Ann Ophthalmol. 1982 Dec;14(12):1132–1136. [PubMed] [Google Scholar]
- Henderson J. W., Farrow G. M. Malignant melanoma primary in the orbit: report of a case. Trans Am Acad Ophthalmol Otolaryngol. 1972 Nov-Dec;76(6):1487–1490. [PubMed] [Google Scholar]
- Jakobiec F. A., Bonanno P. A., Sigelman J. Conjunctival adnexal cysts and dermoids. Arch Ophthalmol. 1978 Aug;96(8):1404–1409. doi: 10.1001/archopht.1978.03910060158012. [DOI] [PubMed] [Google Scholar]
- Jakobiec F. A., Ellsworth R., Tannenbaum M. Primary orbital melanoma. Am J Ophthalmol. 1974 Jul;78(1):24–39. doi: 10.1016/0002-9394(74)90005-1. [DOI] [PubMed] [Google Scholar]
- Jay B. Malignant melanoma of the orbit in a case of oculodermal melanosis. (Naevus of Ota). Br J Ophthalmol. 1965 Jul;49(7):359–363. doi: 10.1136/bjo.49.7.359. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Leff S. R., Henkind P. Rhabdomyosarcoma and late malignant melanoma of the orbit. Ophthalmology. 1983 Oct;90(10):1258–1260. [PubMed] [Google Scholar]
- Rice C. D., Brown H. H. Primary orbital melanoma associated with orbital melanocytosis. Arch Ophthalmol. 1990 Aug;108(8):1130–1134. doi: 10.1001/archopht.1990.01070100086040. [DOI] [PubMed] [Google Scholar]
- Shields J. A., Augsburger J. J., Donoso L. A. Orbital dermoid cyst of conjunctival origin. Am J Ophthalmol. 1986 Jun 15;101(6):726–729. doi: 10.1016/0002-9394(86)90778-6. [DOI] [PubMed] [Google Scholar]
- Shields J. A., Bakewell B., Augsburger J. J., Flanagan J. C. Classification and incidence of space-occupying lesions of the orbit. A survey of 645 biopsies. Arch Ophthalmol. 1984 Nov;102(11):1606–1611. doi: 10.1001/archopht.1984.01040031296011. [DOI] [PubMed] [Google Scholar]
- Wilkes T. D., Uthman E. O., Thornton C. N., Cole R. E. Malignant melanoma of the orbit in a black patient with ocular melanocytosis. Arch Ophthalmol. 1984 Jun;102(6):904–906. doi: 10.1001/archopht.1984.01040030724029. [DOI] [PubMed] [Google Scholar]
- Wolter J. R., Bryson J. M., Blackhurst R. T. Primary orbital melanoma. Eye Ear Nose Throat Mon. 1966 Aug;45(8):64–passim. [PubMed] [Google Scholar]