Skip to main content
PMC home page
The British Journal of Ophthalmology logoLink to The British Journal of Ophthalmology
. 1996 Jan;80(1):40–48. doi: 10.1136/bjo.80.1.40

Analysis of visual field progression in glaucoma.

F W Fitzke 1, R A Hitchings 1, D Poinoosawmy 1, A I McNaught 1, D P Crabb 1
PMCID: PMC505382  PMID: 8664231

Abstract

BACKGROUND: Despite the widespread use of computerised perimetry the diagnosis of visual field deterioration in following glaucoma patients over time remains particularly difficult. A new method of analysis using a novel graphical display of longitudinal field data is presented. METHODS: A linear regression model of the luminance sensitivity at each stimulus location against time of follow up transforms the quantitative data from a series of fields into a colour coded form which illustrates the spatial configuration of change to aid the interpretation of field loss. The method of analysis and the developed computer software (PROGRESSOR) is described. Comparison with STATPAC-2 glaucoma change probability analysis is given including levels of agreement between the techniques using series of fields of 10 eyes from patients with normal tension glaucoma. RESULTS: Examples of this new method compare well with STATPAC-2 analysis. The level of agreement between the techniques to separate progressing from stable retinal locations is good (kappa = 0.62; SE = 0.04). CONCLUSIONS: This new technique, which combines the change in perimetric sensitivity over time with colour coding of significant change into one image may provide an efficient method to detect true progression in glaucomatous field loss.

Full text

PDF
44

Images in this article

41Image
on p.41
43Image
on p.43
45Image
on p.45

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Asman P., Heijl A., Olsson J., Rootzén H. Spatial analyses of glaucomatous visual fields; a comparison with traditional visual field indices. Acta Ophthalmol (Copenh) 1992 Oct;70(5):679–686. doi: 10.1111/j.1755-3768.1992.tb02152.x. [DOI] [PubMed] [Google Scholar]
  2. Crabb D. P., Edgar D. F., Fitzke F. W., McNaught A. I., Wynn H. P. New approach to estimating variability in visual field data using an image processing technique. Br J Ophthalmol. 1995 Mar;79(3):213–217. doi: 10.1136/bjo.79.3.213. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Crick R. P., Newson R. B., Shipley M. J., Blackmore H., Bulpitt C. J. The progress of the visual field in chronic simple glaucoma and ocular hypertension treated topically with pilocarpine or with timolol. Eye (Lond) 1990;4(Pt 4):563–571. doi: 10.1038/eye.1990.78. [DOI] [PubMed] [Google Scholar]
  4. Dunbar Hoskins H., Jr Does computerised perimetry offer practical advances in choice of therapy in the glaucoma patient? Eye (Lond) 1992;6(Pt 1):43–46. doi: 10.1038/eye.1992.7. [DOI] [PubMed] [Google Scholar]
  5. Fitzke F. W., Crabb D. P., McNaught A. I., Edgar D. F., Hitchings R. A. Image processing of computerised visual field data. Br J Ophthalmol. 1995 Mar;79(3):207–212. doi: 10.1136/bjo.79.3.207. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Fitzke F. W., McNaught A. I. The diagnosis of visual field progression in glaucoma. Curr Opin Ophthalmol. 1994 Apr;5(2):110–115. doi: 10.1097/00055735-199404000-00016. [DOI] [PubMed] [Google Scholar]
  7. Hitchings K. Psychophysical testing in glaucoma. Br J Ophthalmol. 1993 Aug;77(8):471–472. doi: 10.1136/bjo.77.8.471. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Holmin C., Krakau C. E. Regression analysis of the central visual field in chronic glaucoma cases. A follow-up study using automatic perimetry. Acta Ophthalmol (Copenh) 1982 Apr;60(2):267–274. doi: 10.1111/j.1755-3768.1982.tb08381.x. [DOI] [PubMed] [Google Scholar]
  9. Johnson C. A. Modern developments in clinical perimetry. Curr Opin Ophthalmol. 1993 Apr;4(2):7–13. [PubMed] [Google Scholar]
  10. Landis J. R., Koch G. G. The measurement of observer agreement for categorical data. Biometrics. 1977 Mar;33(1):159–174. [PubMed] [Google Scholar]
  11. Mikelberg F. S. Do computerised visual fields and automated optic disc analysis assist in the choice of therapy in glaucoma? Eye (Lond) 1992;6(Pt 1):47–49. doi: 10.1038/eye.1992.8. [DOI] [PubMed] [Google Scholar]
  12. Mikelberg F. S., Drance S. M. The mode of progression of visual field defects in glaucoma. Am J Ophthalmol. 1984 Oct 15;98(4):443–445. doi: 10.1016/0002-9394(84)90128-4. [DOI] [PubMed] [Google Scholar]
  13. Morgan R. K., Feuer W. J., Anderson D. R. Statpac 2 glaucoma change probability. Arch Ophthalmol. 1991 Dec;109(12):1690–1692. doi: 10.1001/archopht.1991.01080120074029. [DOI] [PubMed] [Google Scholar]
  14. Noureddin B. N., Poinoosawmy D., Fietzke F. W., Hitchings R. A. Regression analysis of visual field progression in low tension glaucoma. Br J Ophthalmol. 1991 Aug;75(8):493–495. doi: 10.1136/bjo.75.8.493. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. O'Brien C., Schwartz B., Takamoto T., Wu D. C. Intraocular pressure and the rate of visual field loss in chronic open-angle glaucoma. Am J Ophthalmol. 1991 Apr 15;111(4):491–500. doi: 10.1016/s0002-9394(14)72386-4. [DOI] [PubMed] [Google Scholar]
  16. O'Brien C., Schwartz B. The visual field in chronic open angle glaucoma: the rate of change in different regions of the field. Eye (Lond) 1990;4(Pt 4):557–562. doi: 10.1038/eye.1990.77. [DOI] [PubMed] [Google Scholar]
  17. O'Shea R. P., McDonald A. A., Cumming A., Peart D., Sanderson G., Molteno A. C. Interocular transfer of the movement aftereffect in central and peripheral vision of people with strabismus. Invest Ophthalmol Vis Sci. 1994 Jan;35(1):313–317. [PubMed] [Google Scholar]
  18. Spenceley S. E., Henson D. B., Bull D. R. Visual field analysis using artificial neural networks. Ophthalmic Physiol Opt. 1994 Jul;14(3):239–248. doi: 10.1111/j.1475-1313.1994.tb00004.x. [DOI] [PubMed] [Google Scholar]
  19. Vogel R., Crick R. P., Mills K. B., Reynolds P. M., Sass W., Clineschmidt C. M., Tipping R. Effect of timolol versus pilocarpine on visual field progression in patients with primary open-angle glaucoma. Ophthalmology. 1992 Oct;99(10):1505–1511. doi: 10.1016/s0161-6420(92)31773-7. [DOI] [PubMed] [Google Scholar]
  20. Weber J., Koll W., Krieglstein G. K. Intraocular pressure and visual field decay in chronic glaucoma. Ger J Ophthalmol. 1993 May;2(3):165–169. [PubMed] [Google Scholar]
  21. Wild J. M., Hussey M. K., Flanagan J. G., Trope G. E. Pointwise topographical and longitudinal modeling of the visual field in glaucoma. Invest Ophthalmol Vis Sci. 1993 May;34(6):1907–1916. [PubMed] [Google Scholar]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Publishing Group

RESOURCES