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. 1966 Jun;50(6):325–384. doi: 10.1136/bjo.50.6.325

II. Ultrastructural changes in focal retinal ischaemia.

M Shakib, N Ashton
PMCID: PMC506239  PMID: 6006933

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ADAMS W. R., PRINCE A. F. Cellular changes associated with infection of the Ehrlich ascites tumor with Newcastle disease virus. Ann N Y Acad Sci. 1959 Jul 21;81:89–100. doi: 10.1111/j.1749-6632.1959.tb49298.x. [DOI] [PubMed] [Google Scholar]
  2. ASHTON N. Diabetic retinopathy: a new approach. Lancet. 1959 Oct 24;2(7104):625–630. doi: 10.1016/s0140-6736(59)91407-2. [DOI] [PubMed] [Google Scholar]
  3. Abercrombie M., Johnson M. L. Quantitative histology of Wallerian degeneration: I. Nuclear population in rabbit sciatic nerve. J Anat. 1946 Jan;80(Pt 1):37–50. [PMC free article] [PubMed] [Google Scholar]
  4. Ashton N., Pears M. A., Pickering G. W. NEURORETINOPATHY FOLLOWING HAEMORRHAGE WITH A DISCUSSION ON THE NATURE OF CYTOID BODIES. Br J Ophthalmol. 1961 Jun;45(6):385–394. doi: 10.1136/bjo.45.6.385. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. BARTON A. A., CAUSEY G. Electron microscopic study of the superior cervical ganglion. J Anat. 1958 Jul;92(3):399–407. [PMC free article] [PubMed] [Google Scholar]
  6. BEAUFAY H., DE DUVE C. Tissue fractionation studies. 9. Enzymic release of bound hydrolases. Biochem J. 1959 Dec;73:604–609. doi: 10.1042/bj0730604. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. BERGSTRAND A., BUCHT H. The glomerular lesions of diabetes mellitus and their electron-microscope appearances. J Pathol Bacteriol. 1959 Jan;77(1):231–242. doi: 10.1002/path.1700770122. [DOI] [PubMed] [Google Scholar]
  8. BUBIS J. J., LUSE S. A. AN ELECTRON MICROSCOPIC STUDY OF EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS IN THE RAT. Am J Pathol. 1964 Feb;44:299–317. [PMC free article] [PubMed] [Google Scholar]
  9. BUNGE R. P., BUNGE M. B., RISH Electron microscopic study of demyelination in an experimentally induced lesion in adult cat spinal cord. J Biophys Biochem Cytol. 1960 Jul;7:685–696. doi: 10.1083/jcb.7.4.685. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Bloodworth J. M., Jr, Molitor D. L. Ultrastructural aspects of human and canine diabetic retinopathy. Invest Ophthalmol. 1965 Dec;4(6):1037–1048. [PubMed] [Google Scholar]
  11. CAULFIELD J., KLIONSKY B. Myocardial ischemia and early infarction: an electron microscopic study. Am J Pathol. 1959 May-Jun;35(3):489–523. [PMC free article] [PubMed] [Google Scholar]
  12. CAUSEY G., HOFFMAN H. Cytoplasmic synthesis in nerve cells. Br J Cancer. 1955 Dec;9(4):666–673. doi: 10.1038/bjc.1955.72. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. CAVANAGH J. B. The toxic effects of triortho-cresyl phosphate on the nervous system; an experimental study in hens. J Neurol Neurosurg Psychiatry. 1954 Aug;17(3):163–172. doi: 10.1136/jnnp.17.3.163. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. CHRISTENSEN L. The nature of the cytoid body. Trans Am Ophthalmol Soc. 1958;56:451–473. [PMC free article] [PubMed] [Google Scholar]
  15. COGAN D. G. Retinal architecture and pathophysiology. Am J Ophthalmol. 1962 Sep;54:347–363. doi: 10.1016/0002-9394(62)93751-0. [DOI] [PubMed] [Google Scholar]
  16. CONFER D. B., STENGER R. J. THE EVOLUTION OF LYSOSOMES IN HYPOXIC LIVER PARENCHYMA AS SEEN WITH THE ELECTRON MICROSCOPE. Am J Pathol. 1964 Oct;45:533–546. [PMC free article] [PubMed] [Google Scholar]
  17. D AGOSTINO A. N. AN ELECTRON MICROSCOPIC STUDY OF THE TRIGEMINAL GANGLION OF THE RAT POISONED BY PLASMOCIDE. Neurology. 1964 Feb;14:114–124. doi: 10.1212/wnl.14.2.114. [DOI] [PubMed] [Google Scholar]
  18. DAVISON P. F., TAYLOR E. W. Physical-chemical studies of proteins of squid nerve axoplasm, with special reference to the axon fibrous protein. J Gen Physiol. 1960 Mar;43:801–823. doi: 10.1085/jgp.43.4.801. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. DAVSON H., SPAZIANI E. The blood-brain barrier and the extracellular space of brain. J Physiol. 1959 Dec;149:135–143. doi: 10.1113/jphysiol.1959.sp006330. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. DE DUVE C., BEAUFAY H. Tissue fractionation studies. 10. Influence of ischaemia on the state of some bound enzymes in rat liver. Biochem J. 1959 Dec;73:610–616. doi: 10.1042/bj0730610. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. DE ROBERTIS E. Submicroscopic changes of the synapse after nerve section in the acoustic ganglion of the guinea pig; an electron microscope study. J Biophys Biochem Cytol. 1956 Sep 25;2(5):503–512. doi: 10.1083/jcb.2.5.503. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. DOLLERY C. T., HODGE J. V., ENGEL M. Studies of the retinal circulation with flourescein. Br Med J. 1962 Nov 10;2(5314):1210–1215. doi: 10.1136/bmj.2.5314.1210. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. ESTABLE C., ACOSTA-FERREIRA W., SOTELO J. R. An electron microscope study of the regenerating nerve fibers. Z Zellforsch Mikrosk Anat. 1957;46(4):387–399. doi: 10.1007/BF00345052. [DOI] [PubMed] [Google Scholar]
  24. FINE B. S., ZIMMERMAN L. E. Muller's cells and the "middle limiting membrane" of the human retina. An electron microscopic study. Invest Ophthalmol. 1962 Jun;1:304–326. [PubMed] [Google Scholar]
  25. GONATAS N. K., TERRY R. D., WINKLER R., KOREY S. R., GOMEZ C. J., STEIN A. A CASE OF JUVENILE LIPIDOSIS: THE SIGNIFICANCE OF ELECTRON MICROSCOPIC AND BIOCHEMICAL OBSERVATIONS OF A CEREBRAL BIOPSY. J Neuropathol Exp Neurol. 1963 Oct;22:557–580. [PubMed] [Google Scholar]
  26. Gonatas N. K., Levine S., Shoulson R. Phagocytosis and regeneration of myelin in an experimental leukoencephalopathy. Am J Pathol. 1964 Apr;44(4):565–583. [PMC free article] [PubMed] [Google Scholar]
  27. Gray E. G., Hamlyn L. H. Electron microscopy of experimental degeneration in the avian optic tectum. J Anat. 1962 Jul;96(Pt 3):309–316.5. [PMC free article] [PubMed] [Google Scholar]
  28. HARTMANN J. F. Electron microscopy of motor nerve cells following section of axones. Anat Rec. 1954 Jan;118(1):19–33. doi: 10.1002/ar.1091180103. [DOI] [PubMed] [Google Scholar]
  29. HELANDER H. F. A preliminary note on the ultrastructure of the argyrophile cells of the mouse gastric mucosa. J Ultrastruct Res. 1961 Jun;5:257–262. doi: 10.1016/s0022-5320(61)90019-3. [DOI] [PubMed] [Google Scholar]
  30. HOGAN M. J., FEENEY L. THE ULTRASTRUCTURE OF THE RETINAL VESSELS. III. VASCULAR-GLIAL RELATIONSHIPS. J Ultrastruct Res. 1963 Aug;49:47–64. doi: 10.1016/s0022-5320(63)80035-0. [DOI] [PubMed] [Google Scholar]
  31. HUDSON G., HARTMANN J. F. The relationship between dense bodies and mitochondria in motor neurones. Z Zellforsch Mikrosk Anat. 1961;54:147–157. doi: 10.1007/BF00338699. [DOI] [PubMed] [Google Scholar]
  32. Hills C. P. Ultrastructural changes in the capillary bed of the rat cerebral cortex in anoxic-ischemic brain lesions. Am J Pathol. 1964 Apr;44(4):531–551. [PMC free article] [PubMed] [Google Scholar]
  33. JOHNSON A. C., McNABB A. R., ROSSITER R. J. Chemistry of wallerian degeneration; a review of recent studies. Arch Neurol Psychiatry. 1950 Jul;64(1):105–121. doi: 10.1001/archneurpsyc.1950.02310250111010. [DOI] [PubMed] [Google Scholar]
  34. Jablonski W., Meyer H. The occurrence of wandering cells in cultures of nervous tissue in vitro, and the changes in their form in various media. J Anat. 1938 Oct;73(Pt 1):130–134.1. [PMC free article] [PubMed] [Google Scholar]
  35. KARRER H. E. Electron microscopic study of the phagocytosis process in lung. J Biophys Biochem Cytol. 1960 Apr;7:357–366. doi: 10.1083/jcb.7.2.357. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. KONIGSMARK B. W., SIDMAN R. L. ORIGIN OF BRAIN MACROPHAGES IN THE MOUSE. J Neuropathol Exp Neurol. 1963 Oct;22:643–676. doi: 10.1097/00005072-196310000-00006. [DOI] [PubMed] [Google Scholar]
  37. LAMPERT P., BLUMBERG J. M., PENTSCHEW A. AN ELECTRON MICROSCOPIC STUDY OF DYSTROPHIC AXONS IN THE GRACILE AND CUNEATE NUCLEI OF VITAMIN E-DEFICIENT RATS. J Neuropathol Exp Neurol. 1964 Jan;23:60–77. doi: 10.1097/00005072-196401000-00005. [DOI] [PubMed] [Google Scholar]
  38. LEE J. C. Electron microscopy of Wallerian degeneration. J Comp Neurol. 1963 Feb;120:65–79. doi: 10.1002/cne.901200107. [DOI] [PubMed] [Google Scholar]
  39. LUSE S. Ultrastructure of reactive and neoplastic astrocytes. Lab Invest. 1958 Jul-Aug;7(4):401–417. [PubMed] [Google Scholar]
  40. MAJNO G., KARNOVSKY M. L. A biochemical and morphologic study of myelination and demyelination. III. Effect of an organo-phosphorus compound (Mipafox) on the biosynthesis of lipid by nervous tissue of rats and hens. J Neurochem. 1961 Oct;8:1–16. doi: 10.1111/j.1471-4159.1961.tb13521.x. [DOI] [PubMed] [Google Scholar]
  41. MCGEE W. G., ASHWORTH C. T. FINE STRUCTURE OF CHRONIC HYPERTENSIVE ARTERIOPATHY IN THE HUMAN KIDNEY. Am J Pathol. 1963 Aug;43:273–299. [PMC free article] [PubMed] [Google Scholar]
  42. OHMI S. Electron microscopic study of wallerian degeneration of the peripheral nerve. Z Zellforsch Mikrosk Anat. 1961;54:39–67. doi: 10.1007/BF00384198. [DOI] [PubMed] [Google Scholar]
  43. REINECKE R. D., KUWABARA T., COGAN D. G., WEIS D. R. Retinal vascular patterns. V. Experimental ischemia of the cat eye. Arch Ophthalmol. 1962 Apr;67:470–475. doi: 10.1001/archopht.1962.00960020470015. [DOI] [PubMed] [Google Scholar]
  44. ROBERTSON D. M., VOGEL F. S. Concentric lamination of glial processes in oligodendrogliomas. J Cell Biol. 1962 Nov;15:313–334. doi: 10.1083/jcb.15.2.313. [DOI] [PMC free article] [PubMed] [Google Scholar]
  45. ROBERTSON J. D., BODENHEIMER T. S., STAGE D. E. THE ULTRASTRUCTURE OF MAUTHNER CELL SYNAPSES AND NODES IN GOLDFISH BRAINS. J Cell Biol. 1963 Oct;19:159–199. doi: 10.1083/jcb.19.1.159. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. SAMUELS S., GONATAS N. K., WEISS M. FORMATION OF THE MEMBRANOUS CYTOPLASMIC BODIES IN TAY-SACHS DISEASE: AN IN VITRO STUDY. J Neuropathol Exp Neurol. 1965 Apr;24:256–264. doi: 10.1097/00005072-196504000-00007. [DOI] [PubMed] [Google Scholar]
  47. SCHLAEPFER W. W., HAGER H. ULTRASTRUCTURAL STUDIES OF INH-INDUCED NEUROPATHY IN RATS. II. ALTERATION AND DECOMPOSITION OF THE MYELIN SHEATH. Am J Pathol. 1964 Sep;45:423–433. [PMC free article] [PubMed] [Google Scholar]
  48. SCHULTZ R. L. MACROGLIAL IDENTIFICATION IN ELECTRON MICROGRAPHS. J Comp Neurol. 1964 Apr;122:281–295. doi: 10.1002/cne.901220210. [DOI] [PubMed] [Google Scholar]
  49. STEINER J. W., MIYAI K., PHILLIPS M. J. ELECTRON MICROSCOPY OF MEMBRANE-PARTICLE ARRAYS IN LIVER CELLS OF ETHIONINE-INTOXICATED RATS. Am J Pathol. 1964 Feb;44:169–214. [PMC free article] [PubMed] [Google Scholar]
  50. TAXI J. Etude au microscope électronique de la dégénérescence wallérienne des fibres nerveuses amyéliniques. C R Hebd Seances Acad Sci. 1959 May 11;248(19):2796–2798. [PubMed] [Google Scholar]
  51. TERRY R. D., PENA C. EXPERIMENTAL PRODUCTION OF NEUROFIBRILLARY DEGENERATION 2. ELECTRON MICROSCOPY, PHOSPHATASE HISTOCHEMISTRY AND ELECTRON PROBE ANALYSIS. J Neuropathol Exp Neurol. 1965 Apr;24:200–210. doi: 10.1097/00005072-196504000-00003. [DOI] [PubMed] [Google Scholar]
  52. TRIER J. S. The fine structure of the parathyroid gland. J Biophys Biochem Cytol. 1958 Jan 25;4(1):13–22. doi: 10.1083/jcb.4.1.13. [DOI] [PMC free article] [PubMed] [Google Scholar]
  53. VANHARREVELD A., CROWELL J., MALHOTRA S. K. A STUDY OF EXTRACELLULAR SPACE IN CENTRAL NERVOUS TISSUE BY FREEZE-SUBSTITUTION. J Cell Biol. 1965 Apr;25:117–137. doi: 10.1083/jcb.25.1.117. [DOI] [PMC free article] [PubMed] [Google Scholar]
  54. VIAL J. D. The early changes in the axoplasm during wallerian degeneration. J Biophys Biochem Cytol. 1958 Sep 25;4(5):551–555. doi: 10.1083/jcb.4.5.551. [DOI] [PMC free article] [PubMed] [Google Scholar]
  55. WEBSTER H. D. Transient, focal accumulation of axonal mitochondria during the early stages of wallerian degeneration. J Cell Biol. 1962 Feb;12:361–383. doi: 10.1083/jcb.12.2.361. [DOI] [PMC free article] [PubMed] [Google Scholar]
  56. WIENER J., SPIRO D., LATTES R. G. THE CELLULAR PATHOLOGY OF EXPERIMENTAL HYPERTENSION. II. ARTERIOLAR HYALINOSIS AND FIBRINOID CHANGE. Am J Pathol. 1965 Sep;47:457–485. [PMC free article] [PubMed] [Google Scholar]
  57. YAMASHITA T., ROSEN D. A. Electron-microscopic study of diabetic capillary aneurysm. Arch Ophthalmol. 1962 Jun;67:785–790. doi: 10.1001/archopht.1962.00960020785014. [DOI] [PubMed] [Google Scholar]

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