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. 1970 Jul;25(4):387–398. doi: 10.1136/thx.25.4.387

Furrier's lung

J Cortez Pimentel 1
PMCID: PMC514664  PMID: 5484998

Abstract

As is known, the inhalation of animal hairs can provoke immunological reactions in the respiratory tract affecting the naso-tracheo-bronchial sector and giving rise to asthma-like syndromes. Another form of disease, found in furriers with long exposure to `hair dust', is described. It is characterized by a granulomatous interstitial pneumonia, of the tuberculoid type, very similar to that described in other diseases related to the inhalation of organic dusts, both vegetable and animal, such as `farmer's lung' and `bird fancier's lung'. This new disease—which we experimentally reproduced—can be diagnosed from the occupational history together with the finding on lung biopsy of hair shafts within granulomatous lesions (birefringence and histo-chemical reactions). As in other diseases of this type, a host factor of probable immunological nature is suggested. Attention is drawn to the need to protect workers in the furrier's trade.

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Selected References

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  1. AMSLER R. L'apparition de la tuberculose pulmonaire dans 150 cas de silicose; considérations cliniques, thérapeutiques, médicolégales. Rev Tuberc. 1957 Jun;21(6):612–636. [PubMed] [Google Scholar]
  2. Avila R., Villar T. G. Suberosis. Respiratory disease in cork workers. Lancet. 1968 Mar 23;1(7543):620–621. doi: 10.1016/s0140-6736(68)91239-7. [DOI] [PubMed] [Google Scholar]
  3. CANCELLA L. de C. On a special kind of pneumoconiosis: the suberosis; preliminary report. Med Contemp. 1955 May;73(5):235–242. [PubMed] [Google Scholar]
  4. Cohen H. I., Merigan T. C., Kosek J. C., Eldridge F. Sequoiosis. A granulomatous pneumonitis associated with redwood sawdust inhalation. Am J Med. 1967 Nov;43(5):785–794. doi: 10.1016/0002-9343(67)90121-0. [DOI] [PubMed] [Google Scholar]
  5. DA HORTA J. S., DE CANCELLA L. C. Experimentelle Korkstaubkoniose; experimentelle Suberose. Arch Gewerbepathol Gewerbehyg. 1957;15(4):319–354. [PubMed] [Google Scholar]
  6. EMANUEL D. A., LAWTON B. R., WENZEL F. J. Maple-bark disease. Pneumonitis due to Coniosporium corticale. N Engl J Med. 1962 Feb 15;26:333–337. [PubMed] [Google Scholar]
  7. Filip B., Barborík M. Bronchopulmonální aspergilóza. Prac Lek. 1966 Aug;18(6):308–310. [PubMed] [Google Scholar]
  8. HINSON K. F. W., MOON A. J., PLUMMER N. S. Broncho-pulmonary aspergillosis; a review and a report of eight new cases. Thorax. 1952 Dec;7(4):317–333. doi: 10.1136/thx.7.4.317. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. LONGBOTTOM J. L., PEPYS J. PULMONARY ASPERGILLOSIS: DIAGNOSTIC AND IMMUNOLOGICAL SIGNIFICANCE OF ANTIGENS AND C-SUBSTANCE IN ASPERGILLUS FUMIGATUS. J Pathol Bacteriol. 1964 Jul;88:141–151. doi: 10.1002/path.1700880119. [DOI] [PubMed] [Google Scholar]
  10. Nash E. S., Vogelpoel L., Becker W. B. Pigeon breeder's lung--a case report. S Afr Med J. 1967 Feb 25;41(8):191–193. [PubMed] [Google Scholar]
  11. PEPYS J., LONGBOTTOM J. L., JENKINS P. A. VEGETABLE DUST PNEUMOCONIOSES. IMMUNOLOGIC RESPONSES TO VEGETABLE DUSTS AND THEIR FLORA. Am Rev Respir Dis. 1964 Jun;89:842–858. doi: 10.1164/arrd.1964.89.6.842. [DOI] [PubMed] [Google Scholar]
  12. PEPYS J., RIDDELL R. W., CITRON K. M., CLAYTON Y. M., SHORT E. I. Clinical and immunologic significance of Aspergillus fumigatus in the sputum. Am Rev Respir Dis. 1959 Aug;80:167–180. doi: 10.1164/arrd.1959.80.2.167. [DOI] [PubMed] [Google Scholar]
  13. Pimentel J. C., Marques F. "Vineyard sprayer's lung": a new occupational disease. Thorax. 1969 Nov;24(6):678–688. doi: 10.1136/thx.24.6.678. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Riddle H. F., Channell S., Blyth W., Weir D. M., Lloyd M., Amos W. M., Grant I. W. Allergic alveolitis in a maltworker. Thorax. 1968 May;23(3):271–280. doi: 10.1136/thx.23.3.271. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Seal R. M., Hapke E. J., Thomas G. O., Meek J. C., Hayes M. The pathology of the acute and chronic stages of farmer's lung. Thorax. 1968 Sep;23(5):469–489. doi: 10.1136/thx.23.5.469. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Wettstein P. U. Quantitative Staubuntersuchungen an Silikoselungen schweizerischer Proveinienz. Pathol Microbiol (Basel) 1966;29(1):39–54. [PubMed] [Google Scholar]
  17. van Toorn D. W. Coffee worker's lung. A new example of extrinsic allergic alveolitis. Thorax. 1970 Jul;25(4):399–405. doi: 10.1136/thx.25.4.399. [DOI] [PMC free article] [PubMed] [Google Scholar]

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