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. 1976 Apr;18(1):356–360. doi: 10.1128/jvi.18.1.356-360.1976

Influenza virus RNA's in the cytoplasm of chicken embryo cells treated with 3'-deoxyadenosine.

C L Pridgen
PMCID: PMC515554  PMID: 943576

Abstract

3'-Deoxyadenosine (75 to 100 mug/ml) permitted analysis of the cytoplasmic influencza virus-specific RNAs synthesized early in the replicative cycle-a phase that has hitherto been obscurred by host cell RNA synthesis. In addition, late in the cycle (6 to 8) complementary virus-specific RNA's were the predominantly labeled species, suggesting that higher concentrations of 3'-deoxyadenosine selectively inhibit influenza viral genome replication.

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Selected References

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