Skip to main content
PMC home page
Journal of Virology logoLink to Journal of Virology
. 1977 Jun;22(3):734–741. doi: 10.1128/jvi.22.3.734-741.1977

Replication of herpesvirus DNA. III. Rate of DNA elongation.

T Ben-Porat, M L Blankenship, J M DeMarchi, A S Kaplan
PMCID: PMC515773  PMID: 195088

Abstract

The rate of pseudorabies virus DNA elongation was measured by three different techniques: density shift experiments, radioautography examined by light microscopy, and radioautography examined by electron microscopy. The rate of the fork movement at 37 degrees C was estimated to be approximately 1 micron/min.

Full text

PDF
741

Images in this article

738Image
on p.738
740Image
on p.740

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ben-Porat T., Kaplan A. S., Stehn B., Rubenstein A. S. Concatemeric forms of intracellular herpesvirus DNA. Virology. 1976 Feb;69(2):547–560. doi: 10.1016/0042-6822(76)90484-0. [DOI] [PubMed] [Google Scholar]
  2. Ben-Porat T., Stehn B., Kaplan A. S. Fate of parental herpesvirus DNA. Virology. 1976 Jun;71(2):412–422. doi: 10.1016/0042-6822(76)90369-x. [DOI] [PubMed] [Google Scholar]
  3. Callan H. G. Replication of DNA in the chromosomes of eukaryotes. Proc R Soc Lond B Biol Sci. 1972 Apr 18;181(1062):19–41. doi: 10.1098/rspb.1972.0039. [DOI] [PubMed] [Google Scholar]
  4. EAGLE H. Amino acid metabolism in mammalian cell cultures. Science. 1959 Aug 21;130(3373):432–437. doi: 10.1126/science.130.3373.432. [DOI] [PubMed] [Google Scholar]
  5. Hand R., Tamm I. Initiation of DNA replication in mammalian cells and its inhibition by reovirus infection. J Mol Biol. 1974 Jan 15;82(2):175–183. doi: 10.1016/0022-2836(74)90339-8. [DOI] [PubMed] [Google Scholar]
  6. Hori T., Lark K. G. Effect of puromycin on DNA replication in Chinese hamster cells. J Mol Biol. 1973 Jul 5;77(3):391–404. doi: 10.1016/0022-2836(73)90446-4. [DOI] [PubMed] [Google Scholar]
  7. Huberman J. A., Riggs A. D. On the mechanism of DNA replication in mammalian chromosomes. J Mol Biol. 1968 Mar 14;32(2):327–341. doi: 10.1016/0022-2836(68)90013-2. [DOI] [PubMed] [Google Scholar]
  8. Huberman J. A., Tsai A. Direction of DNA replication in mammalian cells. J Mol Biol. 1973 Mar 25;75(1):5–12. doi: 10.1016/0022-2836(73)90525-1. [DOI] [PubMed] [Google Scholar]
  9. Jean J. H., Ben-Porat T. Appearance in vivo of single-stranded complementary ends on parental herpesvirus DNA. Proc Natl Acad Sci U S A. 1976 Aug;73(8):2674–2678. doi: 10.1073/pnas.73.8.2674. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. KAPLAN A. S., BEN-PORAT T. The action of 5-fluorouracil on the nucleic acid metabolism of pseudorabies virus-infected and noninfected rabbit kidney cells. Virology. 1961 Jan;13:78–92. doi: 10.1016/0042-6822(61)90034-4. [DOI] [PubMed] [Google Scholar]
  11. KAPLAN A. S., VATTER A. E. A comparison of herpes simplex and pseudorabies viruses. Virology. 1959 Apr;7(4):394–407. doi: 10.1016/0042-6822(59)90068-6. [DOI] [PubMed] [Google Scholar]
  12. Painter R. B., Schaefer A. W. Rate of synthesis along replicons of different kinds of mammalian cells. J Mol Biol. 1969 Nov 14;45(3):467–479. doi: 10.1016/0022-2836(69)90306-4. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Virology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES