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. 2013 Dec 9:1–30. doi: 10.1895/wormbook.1.7.2

Wnt signaling in C. elegans.

Hitoshi Sawa, Hendrik C Korswagen
PMCID: PMC5402212  PMID: 25263666

Abstract

Wnt proteins are secreted lipid-modified glycoproteins that control many aspects of development in organisms ranging from sponges to vertebrates. Wnt proteins are also important regulators of C. elegans development, with functions in processes as diverse as cell fate specification, asymmetric cell division, cell migration and synapse formation. In this review, we will give an overview of what we currently know about the signaling mechanisms that mediate these different functions of Wnt.


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