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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1990 Aug;87(15):5856–5857. doi: 10.1073/pnas.87.15.5856

Diffusion-controlled ligand binding to spheres partially covered by receptors: an effective medium treatment.

R Zwanzig 1
PMCID: PMC54427  PMID: 2165606

Abstract

An effective medium treatment is used to extend Berg and Purcell's theory of diffusion-controlled ligand binding to a sphere partially covered by receptors. This treatment takes into account more completely the effects of interference between receptors. The results are in excellent agreement with computer simulations by Northrup.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Berg H. C., Purcell E. M. Physics of chemoreception. Biophys J. 1977 Nov;20(2):193–219. doi: 10.1016/S0006-3495(77)85544-6. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Hill T. L. Effect of rotation on the diffusion-controlled rate of ligand-protein association. Proc Natl Acad Sci U S A. 1975 Dec;72(12):4918–4922. doi: 10.1073/pnas.72.12.4918. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Shoup D., Szabo A. Role of diffusion in ligand binding to macromolecules and cell-bound receptors. Biophys J. 1982 Oct;40(1):33–39. doi: 10.1016/S0006-3495(82)84455-X. [DOI] [PMC free article] [PubMed] [Google Scholar]

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