Abstract
The isolation and characterization of antibiotic U-21,963 are discussed. This compound is a highly unsaturated monobasic acid with the molecular formula C9H7NO3. The molecular weight is 177. It is dextrorotatory, [α]D = +138°, and has a pKa of 5.1. The ultraviolet absorption spectrum, which showed a maximum at 223 mμ (ε = 15,115), indicates unsaturation α-β to the carboxyl group, and the infrared spectrum suggests the presence of an acetylenic group. Explosive decomposition of U-21,963 at 97 C conforms with the latter. U-21,963 is relatively insoluble in water, but readily soluble in ethyl alcohol, acetone, and halogenated hydrocarbons.
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Selected References
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