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. 1967 Mar;15(2):334–339. doi: 10.1128/am.15.2.334-339.1967

Killing of Cells in Bacterial Colonies

Dale E Hunt 1, Robert F Pittillo 1
PMCID: PMC546901  PMID: 4961770

Abstract

Bacterial colonies grown on membrane filters and transferred to plates of inhibitor-containing medium decrease in number of total viable colony-forming cells. The decrease in viable cell count occurs in direct proportion to the concentration of inhibitor present and the length of time the colonies are exposed to the inhibitor, suggesting that the kinetics of cell kill approximate a first-order chemical reaction.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Pittillo R. F., Schabel F. M., Jr, Wilcox W. S., Skipper H. E. Experimental evaluation of potential anticancer agents. XVI. Basic study of effects of certain anticancer agents on kinetic behavior of model bacterial cell populations. Cancer Chemother Rep. 1965 Aug;47:1–26. [PubMed] [Google Scholar]
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