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. 1967 Jul;15(4):808–814. doi: 10.1128/am.15.4.808-814.1967

Etiology of Bacteremia

Harry P Dalton 1, Marvin J Allison 1
PMCID: PMC547070  PMID: 4860529

Abstract

Blood-culture results for a 15-year period from a large southern hospital were tabulated and analyzed for alterations in the bacterial species associated with bacteremia. From 15,543 cultures, 2,410 positive cultures (15.6%) were obtained. These results were grouped into 5-year periods, and an alteration in the incidence of the agents was demonstrated. In the past 5 years, gram-negative bacilli have replaced gram-positive cocci as the most common agents of bacteremia, and several species not formerly associated with septicemia were found to be involved in a large number of cases. The importance of the clinical laboratory monitoring blood culture results was demonstrated as was the need for constant collaboration between the clinician and microbiologist.

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Selected References

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  1. ALBITES V. E., AMSTERDAM D. ENDOCARDITIS DUE TO ESCHERICHIA FREUNDII AND STAPHYLOCOCCUS AUREUS. N Y State J Med. 1965 Feb 1;65:451–455. [PubMed] [Google Scholar]
  2. AUSTRIAN R., GOLD J. PNEUMOCOCCAL BACTEREMIA WITH ESPECIAL REFERENCE TO BACTEREMIC PNEUMOCOCCAL PNEUMONIA. Ann Intern Med. 1964 May;60:759–776. doi: 10.7326/0003-4819-60-5-759. [DOI] [PubMed] [Google Scholar]
  3. Allison M. J., Gerszten E., Dalton H. P. Bacterial endocarditis: pathogenesis and racial susceptibility. South Med J. 1967 Feb;60(2):129–134. doi: 10.1097/00007611-196702000-00005. [DOI] [PubMed] [Google Scholar]
  4. BELLI J., WAISBREN B. A. The number of blood cultures necessary to diagnose most cases of bacterial endocarditis. Am J Med Sci. 1956 Sep;232(3):284–288. doi: 10.1097/00000441-195609000-00006. [DOI] [PubMed] [Google Scholar]
  5. BORNSTEIN D. L., WEINBERG N., SWARTZ M. N., KUNZ L. J. ANAEROBIC INFECTIONS--REVIEW OF CURRENT EXPERIENCE. Medicine (Baltimore) 1964 May;43:207–232. doi: 10.1097/00005792-196405000-00003. [DOI] [PubMed] [Google Scholar]
  6. BRANDT L., SWAHN B. Subacute bacterial endocarditis due to coagulase-negative Staphylococcus albus. Acta Med Scand. 1960 Feb 17;166:125–132. doi: 10.1111/j.0954-6820.1960.tb17362.x. [DOI] [PubMed] [Google Scholar]
  7. CANIPE T. L., HUDSPETH A. S. GAS GANGRENE SEPTICEMIA; REPORT OF AN UNUSUAL CASE. Arch Surg. 1964 Sep;89:544–545. doi: 10.1001/archsurg.1964.01320030134023. [DOI] [PubMed] [Google Scholar]
  8. COX R., SOCKWELL G., LANDERS B. Bacillus subtilis septicemia: report of a case and review of the literature. N Engl J Med. 1959 Oct 29;261:894–896. doi: 10.1056/NEJM195910292611804. [DOI] [PubMed] [Google Scholar]
  9. DE TORREGROSA M. V., ORTIZ A. Severe infections in children due to rare gram-negative bacilli (Mima polymorpha and Bacillus anitratum). J Pediatr. 1961 Jul;59:35–41. doi: 10.1016/s0022-3476(61)80206-0. [DOI] [PubMed] [Google Scholar]
  10. FABER V., JESSEN O., ROSENDAL K., ERIKSEN K. R. Staphylococcal bacteraemia. Clinical and bacteriological observations in 201 cases. Br Med J. 1960 Dec 24;2(5216):1832–1836. doi: 10.1136/bmj.2.5216.1832. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. FINLAND M., JONES W. F., Jr, BARNES M. W. Occurrence of serious bacterial infections since introduction of antibacterial agents. J Am Med Assoc. 1959 Aug 29;170:2188–2197. doi: 10.1001/jama.1959.63010180008012. [DOI] [PubMed] [Google Scholar]
  12. HENDERSON J., NICKERSON J. F. BACTERIAL ENDOCARDITIS WITH CANDIDA ALBICANS SUPERINFECTION. Can Med Assoc J. 1964 Feb 15;90:452–458. [PMC free article] [PubMed] [Google Scholar]
  13. HEREDIA A., PRADO VERTIZ A., CARRILLO J. [Septicemia caused by Klebsiella pneumoniae. Study of 5 cases]. Bol Med Hosp Infant Mex. 1960 Nov-Dec;17:899–911. [PubMed] [Google Scholar]
  14. Hochstein H. D., Kirkham W. R., Young V. M. Recovery of more than 1 organism in septicemias. N Engl J Med. 1965 Aug 26;273(9):468–474. doi: 10.1056/NEJM196508262730903. [DOI] [PubMed] [Google Scholar]
  15. KOTIN P. Techniques and interpretation of routine blood cultures; observations in five thousand consecutive patients. J Am Med Assoc. 1952 Aug 2;119(14):1273–1276. doi: 10.1001/jama.1952.02930310009002. [DOI] [PubMed] [Google Scholar]
  16. LEWISOHN M. Micrococcus tetragenus septicemia; report of a case including subacute bacterial endocarditis of the pulmonic valve and mycotic aneurysm, with autopsy findings and review of the literature. AMA Arch Intern Med. 1957 May;99(5):824–832. doi: 10.1001/archinte.1957.00260050152017. [DOI] [PubMed] [Google Scholar]
  17. MARTIN W. J., MCHENRY M. C. BACTEREMIA DUE TO GRAM-NEGATIVE BACILLI. RESUME OF EXPERIENCES IN 303 CASES. J Lancet. 1964 Nov;84:385–394. [PubMed] [Google Scholar]
  18. MARTIN W. J. SOME OBSERVATIONS ON BACTEREMIA DUE TO GRAM-NEGATIVE BACILLI. SD J Med Pharm. 1964 Sep;17:22–30. [PubMed] [Google Scholar]
  19. RANCE C. P., ROY T. E., DONOHUE W. L., SEPP A., ELDER R., FINLAYSON M. An epidemic of septicemia with meningitis and hemorrhagic encephalitis in premature infants. J Pediatr. 1962 Jul;61:24–32. doi: 10.1016/s0022-3476(62)80225-x. [DOI] [PubMed] [Google Scholar]
  20. RAPAPORT S. I., TATTER D., COEUR-BARRON N., HJORT P. F. PSEUDOMONAS SEPTICEMIA WITH INTRAVASCULAR CLOTTING LEADING TO THE GENERALIZED SHWARTZMAN REACTION. N Engl J Med. 1964 Jul 9;271:80–84. doi: 10.1056/NEJM196407092710206. [DOI] [PubMed] [Google Scholar]
  21. REYES H., HURTADO R. SEPTICEMIAS POR BACILOS GRAM-NEGATIVOS. EXPERIENCIA EN 34 CASOS. Rev Med Chil. 1964 Jan;92:20–30. [PubMed] [Google Scholar]
  22. RICH M., ST MARY E. Salmonella subacute bacterial endocarditis. Ann Intern Med. 1956 Jan;44(1):162–166. doi: 10.7326/0003-4819-44-1-162. [DOI] [PubMed] [Google Scholar]
  23. SAXER R. J., WALL R. L., UMLAUF H. J., Jr HERELLEA VAGINICOLA SEPTICEMIA. Clin Pediatr (Phila) 1963 Dec;2:669–675. doi: 10.1177/000992286300201205. [DOI] [PubMed] [Google Scholar]
  24. SCHNEIERSON S. S., HERSCHBERGER C. Blood stream invasion by unusual microorganisms. J Mt Sinai Hosp N Y. 1962 Sep-Oct;29:374–384. [PubMed] [Google Scholar]
  25. SMITH I. M., BEALS P. D., KINGSBURY K. R., HASENCLEVER H. F. Observations on Staphylococcus albus septicemia in mice and men. AMA Arch Intern Med. 1958 Sep;102(3):375–388. doi: 10.1001/archinte.1958.00030010375005. [DOI] [PubMed] [Google Scholar]
  26. TUCKER D. N., SLOTNICK I. J., KING E. O., TYNES B., NICHOLSON J., CREVASSE L. Endocarditis caused by a Pasteurella-like organism; report of four cases. N Engl J Med. 1962 Nov 1;267:913–916. doi: 10.1056/NEJM196211012671804. [DOI] [PubMed] [Google Scholar]
  27. WILSON R., HAMBURGER M. Fifteen years' experience with staphylococcus septicemia in a large city hospital; analysis of fifty-five cases in the Cincinnati General Hospital 1940 to 1954. Am J Med. 1957 Mar;22(3):437–457. doi: 10.1016/0002-9343(57)90099-2. [DOI] [PubMed] [Google Scholar]
  28. WITTLER R. G., MALIZIA W. F., KRAMER P. E., TUCKETT J. D., PRITCHARD H. N., BAKER H. J. Isolation of a Corynebacterium and its transitional forms from a case of subacute bacterial endocarditis treated with antibiotics. J Gen Microbiol. 1960 Oct;23:315–333. doi: 10.1099/00221287-23-2-315. [DOI] [PubMed] [Google Scholar]

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