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. 1968 Oct;16(10):1584–1590. doi: 10.1128/am.16.10.1584-1590.1968

Purine Analogue Sensitivity and Lipase Activity of Leptospires

Russell C Johnson 1, Virginia G Harris 1
PMCID: PMC547707  PMID: 5684206

Abstract

The genus Leptospira can be divided into three groups based on purine analogue sensitivity and lipase (trioleinase) activity. Group 1 contains members of the “parasitic complex” of leptospires which initially cannot grow in media containing 10 μg of 2,6-diaminopurine (DAP) per ml or 200 μg of 8-azaguanine per ml. In addition, leptospires in this group possess lipase activity. Group 2 also contains members of the “parasitic complex” of leptospires. Although these leptospires are similarly sensitive to 8-azaguanine, they differ from group 1 leptospires in that they grow in media containing 10 μg of DAP per ml, and they do not possess detectable lipase activity. Group 3 consists of leptospires belonging to the “biflexa complex.” These leptospires are resistant to both purine analogues and have lipase activity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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