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. 1987 Apr;6(4):1037–1043. doi: 10.1002/j.1460-2075.1987.tb04856.x

Drosophila position-specific antigens resemble the vertebrate fibronectin-receptor family.

M Leptin, R Aebersold, M Wilcox
PMCID: PMC553500  PMID: 2954814

Abstract

The Drosophila position-specific (PS) antigens are a family of cell surface glycoprotein complexes thought to be involved in morphogenesis. Their overall structures and biochemical properties are similar to those of a group of vertebrate receptors, including those for fibronectin, fibrinogen and vitronectin, and also the leukocyte antigens Mac-1, LFA-1 and p150,95 and the VLA family of cell surface antigens. The N-terminal sequences of the alpha subunits of some of these molecules are homologous to the N-terminus of a PS antigen component. The Drosophila PS antigens thus appear to be homologous to these vertebrate receptors.

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