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. 2017 Oct 31;25:188. doi: 10.1016/j.ebiom.2017.10.029

Corrigendum to: “Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers” [EBioMedicine 8 (2016) 117–131]

Anuradha Illendula a,1, Jane Gilmour b,1, Jolanta Grembecka c, Venkata Sesha Srimath Tirumala a, Adam Boulton a, Aravinda Kuntimaddi a, Charles Schmidt a, Lixin Wang e, John A Pulikkan f, Hongliang Zong d, Mahmut Parlak g, Cem Kuscu g, Anna Pickin b, Yunpeng Zhou a, Yan Gao a, Lauren Mishra h, Mazhar Adli g, Lucio H Castilla f, Roger A Rajewski i, Kevin A Janes e, Monica L Guzman d, Constanze Bonifer b, John H Bushweller a,
PMCID: PMC5704058  PMID: 29104075

The authors wish to point out that, in some instances of the text in Results section 3.5, the units of ps-ns and μs-ms to define timescales of residue dynamics were inadvertently switched.

“Interestingly, these changes occur both in the μs-ms timescale dynamics (principally near the benzimidazole ring) as well as on the ps-ns timescale (in the vicinity of the pyridine ring), with the latter perhaps a result of ring flipping of the pyridine ring.” should read “Interestingly, these changes occur both in the ps-ns timescale dynamics (principally near the benzimidazole ring) as well as on the μs-ms timescale (in the vicinity of the pyridine ring), with the latter perhaps a result of ring flipping of the pyridine ring.”

“For Arg131, we observe increased μs-ms timescale dynamics with compound binding.” should read “For Arg131, we observe increased ps-ns timescale dynamics with compound binding.”

“For Asn104, we observe an increase in ps-ns timescale dynamics with compound binding.” should read “For Asn104, we observe an increase in μs-ms timescale dynamics with compound binding.”

Also, the legend for Fig. 3 contains similar inadvertent unit switching.

In the legend for Fig. 3D, “Residues showing increased ps-ns timescale motion are colored red and those showing increased μs-ms timescale motion are colored blue.” should read “Residues showing increased μs-ms timescale motion are colored red and those showing increased ps-ns timescale motion are colored blue.”

In the legend for Fig. 3E, “Red indicates increased ps-ns timescale motion and blue indicates increased μs-ms timescale motion.” should read “Red indicates increased μs-ms timescale motion and blue indicates increased ps-ns timescale motion.”

These errors do not alter the conclusions of the paper.


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