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Pharmacokinetic parameters of linarin following oral administration of linarin (50 mg/kg) alone and in combination with piperine (20 mg/kg) (mean ± SD, n = 5).
| Parameters | Linarin | Linarin + Piperine |
|---|---|---|
| t1/2 (h) | 4.2 ± 1.3 | 4.7 ± 2.8 |
| CLz (L/h/kg) | 556 ± 320 | 118 ± 75 |
| AUC0-t (ng·h/mL) | 106 ± 67 | 554 ± 316 |
| AUC0-∞ (ng·h/mL) | 122 ± 76 | 587 ± 347 |
| Tmax (h) | 0.053 ± 0.027 | 0.200 ± 0.046 |
| Cmax (ng/mL) | 145 ± 32 | 647 ± 96 |
