The authors of Guo et al. (2020) have supplied the following correction to their article “Low‐concentration DMSO Accelerates Skin Wound Healing by Akt/mTOR‐mediated Cell Proliferation and Migration in Diabetic Mice.”
In Figure 1e (which shows the scratch wound healing assay of mouse primary keratinocytes treated with 5‐mM DMSO or vehicle control), a duplication of the image taken as a sample was mistakenly used.
FIGURE 1.
The figure showing the correct scratch wound healing assay is provided below. DMSO showed no direct effect on keratinocyte migration in vitro.
In Figure 5a (which shows the EdU incorporation assay), images taken from the DMSO(−) control group were mistakenly included, instead of the correct image for DMSO(+)/RM(+).
FIGURE 5.
DMFs were co‐treated with or without DMSO (5 mM) and rapamycin (0.1 μM). Data are presented as the mean ± SEM with n = 5 for all groups, analysed by one‐way ANOVA with Kruskal–Wallis test for multiple comparison. Significance level: *P < 0.05, compared with the control group. NS, not significant; DMF, diabetic mouse skin‐derived primary fibroblasts; RM, rapamycin (an mTOR inhibitor).
The figure showing the correct EdU incorporation assay is provided below.
The authors state that in both instances these errors do not affect the conclusions of their study.
Br J Pharmacol. 2020;177:5433 10.1111/bph.15296
REFERENCE
- Guo, W. , Qiu, W. , Ao, X. , Li, W. , He, X. , Ao, L. , … Xu, X. (2020). Low‐concentration DMSO accelerates skin wound healing by Akt/mTOR‐mediated cell proliferation and migration in diabetic mice. British Journal of Pharmacology, 177, 3327–3341. 10.1111/bph.15052 [DOI] [PMC free article] [PubMed] [Google Scholar]