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. 2021 Jan 21;63:103169. doi: 10.1016/j.ebiom.2020.103169

Retraction notice to ‘The antineoplastic drug metformin downregulates YAP by interfering with IRF-1 binding to the YAP promoter in NSCLC’ [EBioMedicine 37 (2018) 188–204]

Dan Jin a,1, Jiwei Guo b,1, Deqiang Wang a, Yan Wu b, Xiaohong Wang c, Yong Gao a, Cuijie Shao a, Xin Xu a, Shuying Tan a
PMCID: PMC7838039  PMID: 33487223

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).

This article has been retracted at the request of the Authors. After publication of the EBioMedicine article [1], several concerns were raised with respect to the veracity of the data. Evidence of image duplication was found within figures relating to the transwell assays, scratch assays, immunohistochemistry images, clone formation assays, and xenografted tumours. Discrepancies were also detected between the published Western blots shown in Figure 1B and the original blots. The corresponding author Jiwei Guo and all co-authors would like to withdraw this article to maintain the integrity of the scientific record. The authors sincerely apologise to the editors and journal readership for these oversights and inconvenience that this may have caused.

EBioMedicine Editors

Reference

  • 1.Jin D. The antineoplastic drug metformin downregulates YAP by interfering with IRF-1 binding to the YAP promoter in NSCLC. EBioMedicine. 2018;37:188–204. doi: 10.1016/j.ebiom.2018.10.044. [DOI] [PMC free article] [PubMed] [Google Scholar] [Retracted]

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